Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.35 |
| ▸ | ITGAV | P06756 | 6/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382332 | 0.94 | ITGB3 (0.37) | ITGB3ITGAVITGA2BADRA2AMCHR1 | |
| SCHEMBL6507434 | 0.94 | DRD2 (0.34) | ITGB3ITGAVITGA2BKDM4EDRD2 | |
| SCHEMBL382456 | 0.88 | ITGB3 (0.47) | ITGB3ITGAVITGA2BADRA2AMCHR1 | |
| SCHEMBL6501603 | 0.87 | RORC (0.37) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL6497814 | 0.86 | ITGB3 (0.41) | ITGB3ITGAVITGA2BADRA2AMCHR1 | |
| SCHEMBL383095 | 0.86 | ITGB3 (0.46) | ITGB3ITGAVITGA2BADRA2AMCHR1 | |
| SCHEMBL383158 | 0.85 | ITGB3 (0.44) | ITGB3ITGAVITGA2BKDM4EDRD2 | |
| SCHEMBL383199 | 0.85 | DRD2 (0.36) | ADRA2AMCHR1KDM4EDRD2DRD3 | |
| SCHEMBL382188 | 0.84 | ITGB3 (0.49) | ITGB3ITGAVITGA2BADRA2ADRD2 | |
| SCHEMBL382204 | 0.84 | ITGB3 (0.39) | ITGB3ITGAVITGA2BADRA2AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | claimed |
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |