Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.36 |
| ▸ | DRD3 | P35462 | 5/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381825 | 0.89 | EPHX2 (0.36) | DRD2DRD3EPHX2ADRA2AMCHR1 | |
| SCHEMBL382204 | 0.86 | ITGB3 (0.39) | DRD2DRD3EPHX2ADRA2AMCHR1 | |
| SCHEMBL383372 | 0.85 | ITGB3 (0.42) | NPY2R | |
| SCHEMBL382792 | 0.85 | ITGB3 (0.35) | DRD2DRD3ADRA2AMCHR1ALDH1A1 | |
| SCHEMBL382612 | 0.84 | GAA (0.37) | MEN1KMT2AALDH1A1AOC3 | |
| SCHEMBL382907 | 0.84 | GRIN2B (0.35) | ADRA2AMCHR1MEN1KMT2AALDH1A1 | |
| SCHEMBL381746 | 0.83 | ITGB3 (0.41) | MEN1KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL382332 | 0.82 | ITGB3 (0.37) | ADRA2AMCHR1 | |
| SCHEMBL381765 | 0.82 | ALDH1A1 (0.46) | DRD2DRD3ALDH1A1KDM4EHTT | |
| SCHEMBL381827 | 0.81 | USP30 (0.45) | DRD2DRD3ADRA2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | claimed |
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |