Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.37 |
| ▸ | ITGAV | P06756 | 8/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507479 | 0.94 | ITGB3 (0.36) | ITGB3ITGAVITGA2BHRH4HRH3 | |
| SCHEMBL382826 | 0.87 | ITGB3 (0.51) | ITGB3ITGAVITGA2BNPY2RALDH1A1 | |
| SCHEMBL6501648 | 0.86 | KAT6A (0.39) | ITGB3ITGAVITGA2BCTSSDRD2 | |
| SCHEMBL6497874 | 0.86 | ITGB3 (0.44) | ITGB3ITGAVITGA2BNPY2RKIF18A | |
| SCHEMBL383098 | 0.85 | ITGB3 (0.50) | ITGB3ITGAVITGA2BNPY2R | |
| SCHEMBL382800 | 0.84 | ITGB3 (0.36) | ITGB3ITGAVITGA2BNPY2RHRH4 | |
| SCHEMBL383161 | 0.83 | ITGB3 (0.47) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL382191 | 0.83 | ITGB3 (0.53) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL382990 | 0.83 | ITGB3 (0.38) | ITGB3ITGAVDRD2DRD3ALDH1A1 | |
| SCHEMBL6500480 | 0.83 | ITGB3 (0.38) | ITGB3ITGAVITGA2BDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |