Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.50 |
| ▸ | ITGAV | P06756 | 8/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.50 |
| ▸ | NPY2R | P49146 | 5/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | USP5 | P45974 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382826 | 0.92 | ITGB3 (0.51) | ITGB3ITGAVITGA2BNPY2R | |
| SCHEMBL382191 | 0.90 | ITGB3 (0.53) | ITGB3ITGAVITGA2B | |
| SCHEMBL6497874 | 0.90 | ITGB3 (0.44) | ITGB3ITGAVITGA2BNPY2REPHX2 | |
| SCHEMBL383161 | 0.88 | ITGB3 (0.47) | ITGB3ITGAVITGA2B | |
| SCHEMBL6499277 | 0.88 | SFRP1 (0.41) | ITGB3ITGAVITGA2B | |
| SCHEMBL383668 | 0.86 | ITGB3 (0.48) | ITGB3ITGAVITGA2B | |
| SCHEMBL382802 | 0.85 | ITGB3 (0.37) | ITGB3ITGAVITGA2BNPY2R | |
| SCHEMBL6500480 | 0.84 | ITGB3 (0.38) | ITGB3ITGAVITGA2B | |
| SCHEMBL383096 | 0.84 | ITGB3 (0.47) | ITGB3ITGAVITGA2BNPY2RP2RY12 | |
| SCHEMBL6498464 | 0.84 | DRD2 (0.39) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |