Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.51 |
| ▸ | ITGAV | P06756 | 8/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | MTTP | P55157 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497874 | 0.94 | ITGB3 (0.44) | ITGB3ITGAVITGA2BPKMLMNA | |
| SCHEMBL383098 | 0.92 | ITGB3 (0.50) | ITGB3ITGAVITGA2BNPY2R | |
| SCHEMBL382191 | 0.90 | ITGB3 (0.53) | ITGB3ITGAVITGA2BPKMALDH1A1 | |
| SCHEMBL382656 | 0.88 | ITGB3 (0.63) | ITGB3ITGAVITGA2BPKMALDH1A1 | |
| SCHEMBL383161 | 0.88 | ITGB3 (0.47) | ITGB3ITGAVITGA2BMAPTATM | |
| SCHEMBL382802 | 0.87 | ITGB3 (0.37) | ITGB3ITGAVITGA2BALDH1A1NPY2R | |
| SCHEMBL6499277 | 0.87 | SFRP1 (0.41) | ITGB3ITGAVITGA2BMAPTKMT2A | |
| SCHEMBL6500480 | 0.87 | ITGB3 (0.38) | ITGB3ITGAVITGA2B | |
| SCHEMBL6507479 | 0.86 | ITGB3 (0.36) | ITGB3ITGAVITGA2B | |
| SCHEMBL383668 | 0.85 | ITGB3 (0.48) | ITGB3ITGAVITGA2BALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |