⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3833558 | 0.77 | MAPT (0.40) | — | |
| SCHEMBL3832982 | 0.75 | CYP2E1 (0.40) | — | |
| SCHEMBL3826017 | 0.73 | MAPT (0.37) | — | |
| SCHEMBL3826698 | 0.69 | MAOA (0.42) | — | |
| SCHEMBL3826699 | 0.68 | MAOA (0.30) | — | |
| SCHEMBL31180345 | 0.67 | IDH1 (0.31) | — | |
| SCHEMBL31180308 | 0.64 | PGR (0.30) | — | |
| SCHEMBL3826803 | 0.63 | ALDH1A1 (0.36) | — | |
| SCHEMBL6530748 | 0.62 | CYP11B2 (0.34) | — | |
| SCHEMBL31180336 | 0.60 | ROCK1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318431-A1 | BENZOXAZINONE AND BENZOXAZEPINONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PFIZER INC. | 2009-12-24 | — | — | US | disclosed |
| EP-1987025-B1 | BENZOXAZINONE AND BENZOXAZEPINONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PFIZER PROD INC (US) | 2009-09-16 | — | — | EP | disclosed |
| EP-1987025-A1 | BENZOXAZINONE AND BENZOXAZEPINONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pfizer Products Incorporated (US) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093904-A1 | BENZOXAZINONE AND BENZOXAZEPINONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PFIZER PRODUCTS INC. (US) | 2007-08-23 | — | — | WO | disclosed |