Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18226728 | 0.81 | KMO (0.36) | CYP11B2CYP11B1PDE3BPDE3AGRM4 | |
| SCHEMBL30336272 | 0.81 | PDE3B (0.35) | CYP11B2CYP11B1PDE3BPDE3AGRM4 | |
| SCHEMBL29209037 | 0.81 | PDE3B (0.35) | CYP11B2CYP11B1PDE3BPDE3AGRM4 | |
| SCHEMBL27434591 | 0.79 | L3MBTL1 (0.36) | CYP11B2CYP11B1ALOX5GABRG2GABRB3 | |
| SCHEMBL6526548 | 0.77 | TERT (0.41) | CYP11B2CYP11B1ALOX5GABRG2GABRB3 | |
| SCHEMBL30336343 | 0.74 | TERT (0.41) | CYP11B2CYP11B1PDE3BPDE3ACHRM1 | |
| SCHEMBL7965147 | 0.74 | CYP11B1 (0.31) | CYP11B2CYP11B1GRM4 | |
| SCHEMBL31180349 | 0.74 | ROCK1 (0.38) | CYP11B2CYP11B1ALOX5GPR55 | |
| SCHEMBL5004930 | 0.73 | BMPR1B (0.42) | — | |
| SCHEMBL3826017 | 0.73 | MAPT (0.37) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082897-A1 | OXAZOLIDINONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-09-09 | — | — | WO | disclosed |