SCHEMBL3830558

SCHEMBL3830558

O=C1c2ccc(Oc3ccc4c(c3)C(=O)N(OS(=O)(=O)c3ccc([N+](=O)[O-])cc3)C4=O)cc2C(=O)N1OS(=O)(=O)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.54
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
KMT2A Q03164 3/20 0.48
VDR P11473 2/20 0.48
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 5/20 0.48
KDM4E B2RXH2 3/20 0.48
MAPT P10636 2/20 0.48
HPGD P15428 2/20 0.48
LPAR3 Q9UBY5 2/20 0.47
LPAR1 Q92633 1/20 0.47
LPAR5 Q9H1C0 1/20 0.47
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
CA9 Q16790 3/20 0.44
CA12 O43570 2/20 0.44
F2 P00734 1/20 0.44
HSPB1 P04792 1/20 0.43
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3829861 0.84 KMT2A (0.68) POLBCYP2C19KMT2AVDRMEN1
SCHEMBL3822702 0.84 VDR (0.68) POLBCYP2C19KMT2AVDRMEN1
SCHEMBL11022400 0.84 KDM4E (0.69) POLBCYP2C19KMT2AVDRMEN1
SCHEMBL11027356 0.83 VDR (0.63) KMT2AVDRMEN1ALDH1A1KDM4E
SCHEMBL3826022 0.83 KDM4E (0.51) POLBCYP2C19KMT2AVDRMEN1
SCHEMBL3844039 0.83 VDR (0.55) POLBCYP2C19KMT2AVDRMEN1
SCHEMBL3824625 0.83 KDM4E (0.58) POLBCYP2C9CYP2C19KMT2AVDR
SCHEMBL3825331 0.83 KDM4E (0.58) POLBCYP2C19KMT2AVDRMEN1
SCHEMBL3824621 0.82 KDM4E (0.71) POLBCYP2C19KMT2AVDRMEN1
SCHEMBL3824481 0.80 KMT2A (0.46) KMT2AVDRMEN1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1449833-B1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION WAKO PURE CHEM IND LTD (JP) 2009-09-09 EP disclosed
US-7374857-B2 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2008-05-20 US disclosed
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2005-02-17 US disclosed
EP-1449833-A1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION Wako Pure Chemical Industries, Ltd. (JP) 2004-08-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition ASIC1, GAR1, RER1 POLB 443/4885CYP2C9 625/4885CYP2C19 1031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.