Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.47 |
| ▸ | ITGAV | P06756 | 6/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.47 |
| ▸ | NPY2R | P49146 | 7/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382824 | 0.92 | ITGB3 (0.48) | ITGB3ITGAVITGA2BNPY2RKMT2A | |
| SCHEMBL382189 | 0.90 | ITGB3 (0.50) | ITGB3ITGAVITGA2BNPY2RDRD2 | |
| SCHEMBL6497838 | 0.90 | ITGB3 (0.42) | ITGB3ITGAVITGA2BNPY2RKMT2A | |
| SCHEMBL383159 | 0.88 | ITGB3 (0.44) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL6499251 | 0.88 | SFRP1 (0.42) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL383666 | 0.86 | ITGB3 (0.46) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL382800 | 0.85 | ITGB3 (0.36) | ITGB3ITGAVITGA2BNPY2RDRD2 | |
| SCHEMBL6500444 | 0.84 | KAT6A (0.39) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL383098 | 0.84 | ITGB3 (0.50) | ITGB3ITGAVITGA2BNPY2RP2RY12 | |
| SCHEMBL6498423 | 0.83 | DRD2 (0.40) | ITGB3ITGAVITGA2BDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |