Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ME2 | P23368 | 1/20 | 0.43 |
| ▸ | ME1 | P48163 | 1/20 | 0.43 |
| ▸ | ME3 | Q16798 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.41 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3823112 | 0.90 | RAB9A (0.52) | HSD17B10MEN1KMT2AME2ME1 | |
| SCHEMBL3823083 | 0.89 | VNN1 (0.48) | HSD17B10PRKAA2KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3825171 | 0.89 | RAB9A (0.53) | KMT2AME2ME1ME3HTR2A | |
| SCHEMBL3830332 | 0.89 | MEN1 (0.45) | MEN1KMT2AME2ME1ME3 | |
| Hydrochloric Acid SCHEMBL3822406 | 0.88 | RAB9A (0.52) | KMT2AME2ME1ME3HTR2A | |
| SCHEMBL4735615 | 0.88 | MAPK14 (0.45) | MEN1KMT2AME2ME1ME3 | |
| SCHEMBL3826946 | 0.87 | SMN1; SMN2 (0.56) | PRKAA2MEN1KMT2AME2ME1 | |
| SCHEMBL8195090 | 0.87 | L3MBTL1 (0.40) | HSD17B10PRKAA2MEN1KMT2AME2 | |
| SCHEMBL3829727 | 0.87 | QPCT (0.43) | HSD17B10PRKAA2MEN1KMT2AME2 | |
| SCHEMBL3825957 | 0.86 | EP300 (0.49) | PRKAA2MEN1KMT2AOPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097379-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-09-09 | — | — | EP | claimed |
| WO-2008073936-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |