Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ME2 | P23368 | 1/20 | 0.39 |
| ▸ | ME1 | P48163 | 1/20 | 0.39 |
| ▸ | ME3 | Q16798 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3829727 | 0.92 | QPCT (0.43) | L3MBTL1QPCTPRKAA2DRD2DRD1 | |
| SCHEMBL3824125 | 0.91 | L3MBTL1 (0.44) | L3MBTL1DRD2DRD1DRD5DRD3 | |
| SCHEMBL3831333 | 0.87 | HSD17B10 (0.49) | L3MBTL1PRKAA2ME2ME1ME3 | |
| SCHEMBL3860025 | 0.86 | L3MBTL1 (0.53) | L3MBTL1DRD2DRD1DRD5DRD3 | |
| SCHEMBL3823083 | 0.85 | VNN1 (0.48) | PRKAA2HSD17B10LMNATP53KMT2A | |
| SCHEMBL3858086 | 0.85 | QPCT (0.43) | QPCTDRD2DRD1DRD5DRD3 | |
| SCHEMBL3823072 | 0.84 | KDM4E (0.45) | L3MBTL1DRD2DRD1DRD5DRD3 | |
| SCHEMBL3830922 | 0.84 | L3MBTL1 (0.43) | L3MBTL1QPCTDRD2DRD1DRD5 | |
| SCHEMBL3823358 | 0.82 | HTR1A (0.40) | QPCTDRD2DRD3PDK1OPRM1 | |
| SCHEMBL3823632 | 0.81 | L3MBTL1 (0.45) | L3MBTL1DRD2DRD1DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073936-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |