Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | ME2 | P23368 | 1/20 | 0.41 |
| ▸ | ME1 | P48163 | 1/20 | 0.41 |
| ▸ | ME3 | Q16798 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830332 | 0.91 | MEN1 (0.45) | MAPK14CXCR2SMN1; SMN2OPRM1OPRK1 | |
| SCHEMBL4738924 | 0.90 | OPRM1 (0.40) | MAPK14CXCR2SMN1; SMN2OPRM1OPRK1 | |
| SCHEMBL3823112 | 0.90 | RAB9A (0.52) | SMN1; SMN2OPRM1OPRK1ME2ME1 | |
| SCHEMBL4736473 | 0.90 | OPRM1 (0.41) | MAPK14CXCR2SMN1; SMN2OPRM1OPRK1 | |
| SCHEMBL4738239 | 0.90 | TSHR (0.49) | MAPK14CXCR2OPRM1OPRK1ME2 | |
| SCHEMBL3826946 | 0.90 | SMN1; SMN2 (0.56) | SMN1; SMN2OPRM1OPRK1ME2ME1 | |
| SCHEMBL3825171 | 0.89 | RAB9A (0.53) | SMN1; SMN2OPRM1OPRK1ME2ME1 | |
| Hydrochloric Acid SCHEMBL3822406 | 0.89 | RAB9A (0.52) | SMN1; SMN2OPRM1OPRK1ME2ME1 | |
| SCHEMBL4737244 | 0.88 | ME2 (0.41) | MAPK14CXCR2SMN1; SMN2OPRM1OPRK1 | |
| SCHEMBL3831333 | 0.88 | HSD17B10 (0.49) | SMN1; SMN2OPRM1OPRK1ME2ME1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |