SCHEMBL383336

SCHEMBL383336

C(=Cc1ccc(-n2nccn2)cc1)c1ccc(-n2nccn2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.35
ALDH1A1 P00352 3/20 0.35
MAPK1 P28482 1/20 0.35
MAPT P10636 9/20 0.35
SMN1; SMN2 Q16637 4/20 0.34
NPC1 O15118 4/20 0.34
RAB9A P51151 4/20 0.34
MEN1 O00255 3/20 0.34
CYP1A2 P05177 3/20 0.34
CYP3A4 P08684 3/20 0.34
CYP2C9 P11712 3/20 0.34
HPGD P15428 3/20 0.34
CYP2C19 P33261 3/20 0.34
KMT2A Q03164 3/20 0.34
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA3 P07451 2/20 0.34
CA4 P22748 2/20 0.34
CA6 P23280 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8525606 0.91 CYP11B1 (0.45) KDM4EALDH1A1MEN1HPGDKMT2A
SCHEMBL1609941 0.81 ALDH1A1 (0.55) KDM4EALDH1A1MAPK1SMN1; SMN2LMNA
SCHEMBL21110577 0.79 FBP1 (0.59) ALDH1A1MAPK1MAPTSMN1; SMN2MEN1
SCHEMBL20497363 0.76 KMT2A (0.42) KDM4EALDH1A1MAPK1MAPTSMN1; SMN2
SCHEMBL3706685 0.72 MAPT (0.45) KDM4EALDH1A1MAPK1MAPTSMN1; SMN2
SCHEMBL3276844 0.72 NTRK1 (0.31) NTRK1
SCHEMBL8166966 0.72 NOTUM (0.45) KDM4EALDH1A1MAPTSMN1; SMN2NPC1
SCHEMBL4451027 0.70 KDM4E (0.52) KDM4EALDH1A1MAPTSMN1; SMN2NPC1
SCHEMBL10653293 0.69 KDM4E (0.72) KDM4EALDH1A1MAPK1MAPTNPC1
SCHEMBL11410050 0.69 KDM4E (0.72) KDM4EALDH1A1MAPK1MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 656 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0026744-B1 MEANS AND PROCESS FOR THE TREATMENT AND THE IMPROVEMENT OF THE APPEARANCE OF TEXTILES CIBA-GEIGY AG (CH) 1982-05-05 EP claimed
US-20240216248-A1 MICROBIAL GLYCOLIPIDS ANALYTICON DISCOVERY GMBH (DE) 2024-07-04 US disclosed
US-20240199980-A1 ALKYLBENZENESULFONATE SURFACTANTS PROCTER & GAMBLE (US) 2024-06-20 US disclosed
CN-118159632-A Perfume and perfume mixture 西姆莱斯股份公司 2024-06-07 CN disclosed
WO-2024088521-A1 DETERGENTS AND CLEANING COMPOSITIONS WITH IMPROVED ANTI-REDEPOSITION PROPERTIES SYMRISE AG (DE) 2024-05-02 WO disclosed
WO-2024088520-A1 LIQUID DETERGENTS AND CLEANING COMPOSITIONS WITH IMPROVED HYDROTROPE POWER SYMRISE AG (DE) 2024-05-02 WO disclosed
WO-2024088522-A1 DETERGENTS WITH IMPROVED DYE TRANSFER INHIBITION SYMRISE AG (DE) 2024-05-02 WO disclosed
US-20240124808-A1 POLYUREA MICROCAPSULES AND LIQUID SURFACTANT SYSTEMS CONTAINING THEM SYMRISE AG (DE) 2024-04-18 US disclosed
EP-3664772-B1 1,2-ALKANEDIOLS AND A PROCESS FOR THEIR PRODUCTION SYMRISE AG (DE) 2024-03-20 EP disclosed
WO-2024051922-A1 A FRAGRANCE MIXTURE (III) SYMRISE AG (DE) 2024-03-14 WO disclosed
WO-1992006160-A1 NONIONIC SURFACTANT SYSTEMS CONTAINING POLYHYDROXY FATTY ACID AMIDES AND ONE OR MORE ADDITIONAL NONIONIC SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1992-04-16 WO disclosed
WO-1992006150-A1 DETERGENT COMPOSITIONS CONTAINING POLYHYDROXY FATTY ACID AMIDE AND ALKYL BENZENE SULFONATE THE PROCTER & GAMBLE COMPANY (US) 1992-04-16 WO disclosed
WO-1992006158-A1 DETERGENT COMPOSITIONS CONTAINING POLYHYDROXY FATTY ACID AMIDE AND ALKYL ALKOXYLATED SULFATE THE PROCTER & GAMBLE COMPANY (US) 1992-04-16 WO disclosed
EP-0456569-A1 Liquid softening and anti-static nonionic detergent composition with soil release promoting pet-poet copolymer Colgate-Palmolive Company (US) 1991-11-13 EP disclosed
EP-0403152-A2 Bleaching composition Kao Corporation (JP) 1990-12-19 EP disclosed
EP-0364880-A2 Detergent composition SUNSTAR INC. (JP) 1990-04-25 EP disclosed
US-4790856-A SYNERGISTIC COLGATE-PALMOLIVE COMPANY (US) 1988-12-13 US disclosed
US-4756845-A Peroxide, cyanopyridine activator, cyanopyridinium salt LION CORPORATION (JP) 1988-07-12 US disclosed
EP-0026744-A1 Means and process for the treatment and the improvement of the appearance of textiles CIBA-GEIGY AG (CH) 1981-04-08 EP disclosed
US-4140641-A NONIONIC SURFACTANT, IMIDAZOLINIUM QUATERNARY COMPOUND COLGATE-PALMOLIVE COMPANY (US) 1979-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240216248-A1 MICROBIAL GLYCOLIPIDS UGCG, SGMS1, GPR119 KDM4E 3662/4885ALDH1A1 1617/4885MAPK1 566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.