Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14961833 | 0.80 | ACLY (0.39) | KDM4EHPGDPOLBCYP3A4ALDH1A1 | |
| SCHEMBL8525606 | 0.79 | CYP11B1 (0.45) | KDM4EHPGDCYP19A1ALDH1A1MEN1 | |
| SCHEMBL30212246 | 0.79 | LTA4H (0.50) | ALDH1A1TSHRNPC1RAB9AMEN1 | |
| SCHEMBL15041062 | 0.76 | P2RX7 (0.41) | KDM4EHPGDPOLBP2RX7ALDH1A1 | |
| SCHEMBL8166966 | 0.72 | NOTUM (0.45) | KDM4EHPGDALDH1A1TSHRMAPT | |
| SCHEMBL3706685 | 0.72 | MAPT (0.45) | KDM4EHPGDPOLBCYP3A4ALDH1A1 | |
| SCHEMBL3276844 | 0.72 | NTRK1 (0.31) | — | |
| SCHEMBL2627223 | 0.71 | MAPT (0.52) | KDM4EPOLBCYP3A4ALDH1A1TSHR | |
| SCHEMBL14812187 | 0.71 | MGLL (0.47) | POLBALDH1A1MEN1KMT2AGAA | |
| SCHEMBL22968426 | 0.71 | KEAP1 (0.52) | POLBALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12570658-B2 | Synthetic methods of making (2H-1, 2, 3-triazol-2-yl) phenyl compounds as orexin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2026-03-10 | — | — | US | claimed |
| CN-114555603-B | Improved synthetic methods for preparing (2H-1, 2, 3-triazol-2-yl) phenyl compounds as orexin receptor modulators | 詹森药业有限公司 | 2025-03-14 | — | — | CN | claimed |
| US-20240368505-A1 | FLUORINE-FREE CLEANING AGENT, PREPARATION METHOD THEREFOR AND USE THEREOF | Tan Kah Kee Innovation Laboratory (CN) | 2024-11-07 | — | — | US | claimed |
| CN-118610578-A | Application of azole-rich compound in lithium ion battery electrolyte, lithium ion battery electrolyte and preparation method of lithium ion battery electrolyte | 仲恺农业工程学院 | 2024-09-06 | — | — | CN | claimed |
| CN-116731798-A | Fluorine-free cleaning agent, and preparation method and application thereof | 嘉庚创新实验室 | 2023-09-12 | — | — | CN | claimed |
| WO-2023133876-A1 | FLUORINE-FREE CLEANING AGENT, PREPARATION METHOD THEREFOR AND USE THEREOF | 嘉庚创新实验室 | 2023-07-20 | — | — | WO | claimed |
| CN-114317127-B | Fluorine-free cleaning agent, and preparation method and application thereof | 嘉庚创新实验室 | 2023-07-04 | — | — | CN | claimed |
| US-20220289754-A1 | IMPROVED SYNTHETIC METHODS OF MAKING (2H-1, 2, 3-TRIAZOL-2-YL) PHENYL COMPOUNDS AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-09-15 | — | — | US | claimed |
| EP-4010325-A1 | IMPROVED SYNTHETIC METHODS OF MAKING (2H-1,2,3-TRIAZOL-2-YL)PHENYL COMPOUNDS AS OREXIN RECEPTOR MODULATORS | Janssen Pharmaceutica NV (BE) | 2022-06-15 | — | — | EP | claimed |
| CN-114555603-A | Improved synthesis for the preparation of (2H-1,2, 3-triazol-2-yl) phenyl compounds as orexin receptor modulators | 詹森药业有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-114317127-A | Fluoride-free cleaning agent, and preparation method and application thereof | 嘉庚创新实验室 | 2022-04-12 | — | — | CN | claimed |
| CN-113637027-B | Phenyl triazole dicarboxylic acid-rhodamine B derivative fluorescent probe and preparation method and application thereof | 海南师范大学 | 2022-04-05 | — | — | CN | claimed |
| CN-106939248-A | Automobile water-based base carbon distribution cleaning combination | 佛山市云系科技有限公司 | 2017-07-11 | — | — | CN | claimed |
| CN-106238096-A | A kind of preparation method that catalyst SBA-15@Schiff's base be can be recycled | 新疆大学 | 2016-12-21 | — | — | CN | claimed |
| WO-2005023939-A1 | LIGHTFAST CYANINE DYE COMPOSITIONS FOR OPTICAL DATA RECORDING | CLARIANT INTERNATIONAL LTD (CH) | 2005-03-17 | — | — | WO | claimed |
| EP-1514906-A1 | Lightfast cyanine dye compositions for optical data recording | CLARIANT INTERNATIONAL LTD. (CH) | 2005-03-16 | — | — | EP | claimed |
| US-5646198-A | MIXTURE INCLUDES POLYMER, BENZOTRIAZOLE OR TRIAZOLE COMPOUND, AND COMPOUND WITH HYDROPHOBIC AND HYDROPHILIC PARTS; STORAGE STABILITY; MARINE STRUCTURES | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1997-07-08 | — | — | US | claimed |
| US-4662905-A | REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE | Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) | 1987-05-05 | — | — | US | claimed |
| JP-58039658-A | — | — | None | — | — | JP | disclosed |
| US-3936456-A | Substituted piperazine dione oxyls and hydroxides and polymer compositions stabilized thereby | CIBY-GEIGY CORPORATION (US) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12570658-B2 | Synthetic methods of making (2H-1, 2, 3-triazol-2-yl) phenyl compounds as orexin receptor modulators | HCRTR2, HCRTR1, HRH1 | KDM4E 1028/4885HPGD 824/4885POLB 3865/4885 |
| US-20220289754-A1 | IMPROVED SYNTHETIC METHODS OF MAKING (2H-1, 2, 3-TRIAZOL-2-YL) PHENYL COMPOUNDS AS OREXIN RECEPTOR MODULATORS | HCRTR2, HCRTR1, HTR3B | KDM4E 528/4885HPGD 863/4885POLB 3996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.