Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.37 |
| ▸ | TUBB | P07437 | 2/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3839281 | 0.84 | KDM4E (0.39) | ALDH1A1PARP10TUBB4ATUBBTUBA3C | |
| SCHEMBL2343430 | 0.81 | MAP2 (0.48) | ALDH1A1MAPTPARP10TUBB4ATUBB | |
| SCHEMBL3839787 | 0.81 | SCN9A (0.43) | ALDH1A1MAPTPARP10GSK3BADK | |
| SCHEMBL3839795 | 0.77 | KDM4E (0.53) | ALDH1A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3839803 | 0.76 | TUBB4A (0.44) | ALDH1A1MAPTPARP10TUBB4ATUBB | |
| SCHEMBL3840006 | 0.76 | MCL1 (0.41) | ALDH1A1MAPTGSK3BADKHPGD | |
| SCHEMBL3836337 | 0.74 | KDM4E (0.41) | ALDH1A1MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL3837499 | 0.74 | HTR6 (0.41) | ALDH1A1MAPTGSK3BADKGABRA1 | |
| SCHEMBL3838681 | 0.74 | KIF11 (0.42) | ALDH1A1MAPTGSK3BADKGABRA1 | |
| SCHEMBL3835352 | 0.72 | HSD17B10 (0.48) | ALDH1A1PARP10GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791537-B1 | 3-ARYLTHIOINDOLE-2-CARBOXAMIDE DERIVATIVES AND ANALOGS THEREOF AS INHIBITORS OF CASEIN KINASE I | AVENTIS PHARMA INC (US) | 2009-10-14 | — | — | EP | claimed |