Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.50 |
| ▸ | NPC1 | O15118 | 11/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4960655 | 0.79 | ADORA3 (0.43) | RAB9ANPC1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL7474495 | 0.72 | AR (0.39) | RAB9ANPC1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL5324075 | 0.72 | NPC1 (0.50) | RAB9ANPC1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL3144177 | 0.72 | RAB9A (0.46) | RAB9ANPC1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL646759 | 0.71 | KDM4E (0.45) | RAB9ANPC1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL7143282 | 0.71 | AR (0.44) | RAB9ANPC1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL3727634 | 0.70 | NPC1 (0.55) | RAB9ANPC1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL29374931 | 0.70 | RAB9A (0.64) | RAB9ANPC1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL170196 | 0.70 | RAB9A (0.64) | RAB9ANPC1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL6256201 | 0.69 | MAPT (0.44) | RAB9ANPC1ALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9849119-B2 | Opioid receptor ligands and methods of using and making same | TREVENA, INC. (US) | 2017-12-26 | — | — | US | disclosed |
| EP-1940844-B1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2009-09-30 | — | — | EP | disclosed |
| US-6440961-B1 | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2002-08-27 | — | — | US | disclosed |