SCHEMBL3836698

SCHEMBL3836698

Clc1cc(Cl)c2ccccc2c1Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.55
CYP2A6 P11509 4/20 0.55
CYP3A4 P08684 2/20 0.45
NR4A2 P43354 1/20 0.42
ALDH1A1 P00352 4/20 0.42
MAPT P10636 4/20 0.42
AHR P35869 3/20 0.42
HSD17B10 Q99714 3/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
HPGD P15428 2/20 0.42
KDM4E B2RXH2 2/20 0.42
HTT P42858 2/20 0.42
PKM P14618 1/20 0.42
LMNA P02545 3/20 0.40
TSHR P16473 2/20 0.40
CASP1 P29466 1/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
TP53 P04637 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29829350 1.00 CYP1A2 (0.55) CYP1A2CYP2A6CYP3A4NR4A2ALDH1A1
SCHEMBL10626226 0.79 CYP2A6 (0.55) CYP1A2CYP2A6NR4A2ALDH1A1MAPT
SCHEMBL29720333 0.77 CYP2A6 (0.48) CYP1A2CYP2A6CYP3A4ALDH1A1MAPT
SCHEMBL5488191 0.77 CYP2A6 (0.48) CYP1A2CYP2A6CYP3A4ALDH1A1MAPT
SCHEMBL6684714 0.77 HSD17B10 (0.48) CYP1A2CYP2A6CYP3A4ALDH1A1MAPT
SCHEMBL11797439 0.77 CYP2A6 (0.43) CYP1A2CYP2A6ALDH1A1MAPTAHR
SCHEMBL147819 0.75 MAOA (0.58) CYP1A2CYP2A6ALDH1A1MAPTHSD17B10
SCHEMBL29440644 0.75 MAOA (0.58) CYP1A2CYP2A6ALDH1A1MAPTHSD17B10
SCHEMBL10040170 0.74 CYP1A2 (0.50) CYP1A2CYP2A6CYP3A4NR4A2ALDH1A1
SCHEMBL553501 0.74 ALDH1A1 (0.59) CYP1A2CYP2A6CYP3A4ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552901-B2 Polyarylene sulfide production method KUREHA CORPORATION (JP) 2026-02-17 US disclosed
US-12509555-B2 Method for producing polyarylene sulfide KUREHA CORPORATION (JP) 2025-12-30 US disclosed
US-20230192958-A1 POLYARYLENE SULFIDE PRODUCTION METHOD KUREHA CORPORATION (JP) 2023-06-22 US disclosed
US-20230033026-A1 METHOD FOR PRODUCING POLYARYLENE SULFIDE KUREHA CORPORATION (JP) 2023-02-02 US disclosed
CN-115485320-A Method for producing polyarylene sulfide 株式会社吴羽 2022-12-16 CN disclosed
CN-114787241-A Method for producing polyarylene sulfide 株式会社吴羽 2022-07-22 CN disclosed
WO-2021131985-A1 METHOD FOR PRODUCING POLYARYLENE SULFIDE 株式会社クレハ 2021-07-01 WO disclosed
US-10793584-B2 Naphthobischalcogenadiazole derivative and production method therefor OSAKA UNIVERSITY (JP) 2020-10-06 US disclosed
US-20190337966-A1 NAPHTHOBISCHALCOGENADIAZOLE DERIVATIVE AND PRODUCTION METHOD THEREFOR OSAKA UNIVERSITY (JP) 2019-11-07 US disclosed
EP-3564245-A1 NAPHTHOBISCHALCOGENADIAZOLE DERIVATIVE AND PRODUCTION METHOD THEREFOR Osaka University (JP) 2019-11-06 EP disclosed
EP-0087045-A1 Process for preparing polyarylenesulphides with increased thermal and chemical resistance and improved quality of colour BAYER AG (DE) 1983-08-31 EP disclosed
EP-0087046-A1 Process for preparing polyarylenesulphides with increased thermal and chemical resistance BAYER AG (DE) 1983-08-31 EP disclosed
EP-0023314-B1 PROCESS FOR PREPARING POLY(ARYLENE SULFIDES) BAYER AG (DE) 1983-07-20 EP disclosed
US-4362864-A Process for the preparation of polyarylene sulphides BAYER AKTIENGESELLSCHAFT (DE) 1982-12-07 US disclosed
EP-0065689-A1 Method of producing poly(arylene sulfides) BAYER AG (DE) 1982-12-01 EP disclosed
US-4331801-A Process for the preparation of polyarylene sulphides BAYER AKTIENGESELLSCHAFT (DE) 1982-05-25 US disclosed
EP-0040747-A2 Process for preparing polyarylene sulfides BAYER AG (DE) 1981-12-02 EP disclosed
US-4303781-A Process for the preparation of polyarylene sulphides BAYER AKTIENGESELLSCHAFT (DE) 1981-12-01 US disclosed
EP-0023313-A1 Process for preparing poly(arylene sulfides) BAYER AG (DE) 1981-02-04 EP disclosed
EP-0023314-A1 Process for preparing poly(arylene sulfides) BAYER AG (DE) 1981-02-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10793584-B2 Naphthobischalcogenadiazole derivative and production method therefor CYP24A1, CYP26B1, CYP21A2 CYP1A2 115/4885CYP2A6 96/4885CYP3A4 389/4885
US-20190337966-A1 NAPHTHOBISCHALCOGENADIAZOLE DERIVATIVE AND PRODUCTION METHOD THEREFOR CYP24A1, CYP26B1, CYP21A2 CYP1A2 115/4885CYP2A6 96/4885CYP3A4 389/4885
US-12509555-B2 Method for producing polyarylene sulfide AS3MT, ZW10, POLR2H CYP1A2 2061/4885CYP2A6 3455/4885CYP3A4 1187/4885
US-12552901-B2 Polyarylene sulfide production method PEAK1, POLR2H, TDO2 CYP1A2 704/4885CYP2A6 1765/4885CYP3A4 604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.