Asparagine

Asparagine

SCHEMBL38379

NC(=O)C[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 1/20 0.56
▸ BLM P54132 1/20 0.56
▸ PMP22 Q01453 1/20 0.56
▸ KMT2A Q03164 1/20 0.56
▸ GRIK1 P39086 8/20 0.54
▸ GRIK2 Q13002 5/20 0.54
▸ GRM1 Q13255 2/20 0.54
▸ GRM2 Q14416 2/20 0.54
▸ SLC7A5 Q01650 1/20 0.52
▸ PTGS1 P23219 1/20 0.50
▸ SLC7A11 Q9UPY5 1/20 0.50
▸ GGT1 P19440 4/20 0.48
▸ SLC1A1 P43005 4/20 0.48
▸ GRIA4 P48058 4/20 0.46
▸ GRIK3 Q13003 4/20 0.46
▸ GRIK5 Q16478 4/20 0.46
▸ SLC1A3 P43003 3/20 0.46
▸ SLC1A2 P43004 3/20 0.46
▸ GRIA2 P42262 3/20 0.46
▸ GRIA1 P42261 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Asparagine SCHEMBL30131205 1.00 — —
Asparagine SCHEMBL8827 1.00 — —
Asparagine SCHEMBL30486685 1.00 — —
Asparagine SCHEMBL288094 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL288093 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL4347082 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL15460 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL8826 1.00 — —
Asparagine SCHEMBL150535 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL20489207 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7941 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118307637-A Peptides, compositions comprising the peptides and use of the peptides in the manufacture of a medicament for the treatment of obesity 3H生物有限公司 2024-07-09 — — CN claimed
CN-117737026-A GGPPS muteins related to carotenoid content in wheat kernel 河南农业大学 2024-03-22 — — CN claimed
CN-117630263-A Method for detecting various free amino acids in plasma based on liquid chromatography-tandem mass spectrometry 上海睿质科技有限公司 2024-03-01 — — CN claimed
CN-116200374-A D-carbamoyl hydrolase mutant with improved thermal stability and application thereof in synthesis of D-amino acid 江南大学 2023-06-02 — — CN claimed
CN-116059388-A Polypeptide-chemotherapeutic drug conjugate, preparation method and application thereof 国家纳米科学中心 2023-05-05 — — CN claimed
CN-111549010-B GGPPS directional double-site mutant protein 209-233 中国烟草总公司郑州烟草研究院 2022-10-28 — — CN claimed
CN-111593032-B Directional five-site mutant protein GGPPS on enzyme pocket and enzyme molecule surface 中国烟草总公司郑州烟草研究院 2022-10-28 — — CN claimed
CN-113138206-B Method for identifying amino acid 宁波大学 2022-04-19 — — CN claimed
CN-109206606-B Method for preparing polycarbonate by using ionic liquid catalytic melting transesterification method 华东理工大学 2021-11-12 — — CN claimed
CN-109593188-B Method for preparing polycarbonate based on strong-basicity ionic liquid high-efficiency catalysis 华东理工大学 2021-09-28 — — CN claimed
EP-0400051-A1 POLYPEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY. EASTMAN KODAK CO (US) 1990-12-05 — — EP claimed
WO-1989010933-A1 POLYPEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY EASTMAN KODAK COMPANY (US) 1989-11-16 — — WO claimed
EP-0341767-A1 Immunoenzymatic method in homogeneous phase for the determination of anti-plasmodium falciparum-sporozoite antibodies in human blood ENIRICERCHE S.p.A. (IT) 1989-11-15 — — EP claimed
EP-0328132-A2 Therapeutic agent for thrombocytopenia THE GREEN CROSS CORPORATION (JP) 1989-08-16 — — EP claimed
WO-1989007110-A1 POLYPEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY EASTMAN KODAK COMPANY (US) 1989-08-10 — — WO claimed
US-4843146-A Immunologically active polypeptides useful for the preparation of antimalarial vaccines and of diagnostic kits for the detection of antisporozoite antibodies ENIRICERCHE, S.P.A. (IT) 1989-06-27 — — US claimed
WO-1988009780-A2 POLYPEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY EASTMAN KODAK COMPANY (US) 1988-12-15 — — WO claimed
EP-0293333-A2 A synthetic nonapeptide of use as an adjuvant SCLAVO S.p.A. (IT) 1988-11-30 — — EP claimed
EP-0265847-A2 Monoclonal antibody reacting with TRF (interleukin-5) OLYMPUS OPTICAL CO., LTD. (JP) 1988-05-04 — — EP claimed
EP-0231728-A2 Synthetic peptide with human interleukin 1 activity SCLAVO S.p.A. (IT) 1987-08-12 — — EP claimed
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