Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.47 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37644 | 0.89 | PDE5A (0.53) | PDE5ARNASEH1RAB9AKDM4ELMNA | |
| SCHEMBL37584 | 0.86 | PDE5A (0.66) | PDE5ARAB9AKDM4ELMNASMN1; SMN2 | |
| SCHEMBL38180 | 0.77 | PDE5A (0.60) | PDE5ARNASEH1RAB9AKDM4ELMNA | |
| SCHEMBL38312 | 0.76 | PDE5A (0.70) | PDE5ARAB9AKDM4ELMNASMN1; SMN2 | |
| SCHEMBL37850 | 0.76 | RNASEH1 (0.47) | PDE5ARNASEH1RAB9AKDM4ELMNA | |
| SCHEMBL38977 | 0.74 | RNASEH1 (0.49) | PDE5ARNASEH1RAB9AKDM4ELMNA | |
| SCHEMBL44521 | 0.74 | RAB9A (0.45) | PDE5ARNASEH1RAB9AKDM4ELMNA | |
| SCHEMBL38484 | 0.74 | PDE5A (0.57) | PDE5ARNASEH1RAB9AKDM4ELMNA | |
| SCHEMBL46456 | 0.74 | PDE5A (0.57) | PDE5ARNASEH1RAB9AKDM4ELMNA | |
| SCHEMBL38179 | 0.74 | PDE5A (0.46) | PDE5ARNASEH1RAB9AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004900-A1 | THIENOPYRIMIDINE COMPOUNDS | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2012-01-12 | — | — | WO | disclosed |