Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ERN1 | O75460 | 3/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15065366 | 0.85 | ALDH1A1 (0.59) | ALDH1A1CYP1A2LMNACYP2C9CYP2C19 | |
| SCHEMBL19563634 | 0.85 | ALDH1A1 (0.64) | ALDH1A1CYP1A2LMNACYP2C9CYP2C19 | |
| SCHEMBL19563670 | 0.82 | ALDH1A1 (0.55) | ALDH1A1CYP1A2LMNACYP2C9CYP2C19 | |
| SCHEMBL96291 | 0.81 | ALDH1A1 (1.00) | ALDH1A1CYP1A2CYP2C9CYP2C19TRIM24 | |
| SCHEMBL2419953 | 0.81 | ALDH1A1 (0.61) | ALDH1A1CYP1A2LMNACYP2C9CYP2C19 | |
| SCHEMBL5989078 | 0.81 | HTR2A (0.52) | ALDH1A1CYP1A2LMNACYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL9456784 | 0.79 | ALDH1A1 (0.96) | ALDH1A1CYP1A2CYP2C9CYP2C19TRIM24 | |
| SCHEMBL9400065 | 0.79 | PDE7A (0.54) | ALDH1A1LMNATRIM24TYRTRIM33 | |
| SCHEMBL20346747 | 0.78 | ALDH1A1 (0.63) | ALDH1A1CYP1A2LMNACYP2C9CYP2C19 | |
| SCHEMBL24068855 | 0.78 | ALDH1A1 (0.79) | ALDH1A1CYP1A2LMNACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8884061-B2 | Compositions and methods of use of electron transport system inhibitors | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2014-11-11 | — | — | US | disclosed |
| US-20090030084-A1 | Compositions and Methods of Use of Electron Transport System Inhibitors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030084-A1 | Compositions and Methods of Use of Electron Transport System Inhibitors | ABCB11, SLC8B1, SLC47A1 | ALDH1A1 1221/4885CYP1A2 392/4885LMNA 3436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.