Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 7/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11524084 | 0.83 | SMN1; SMN2 (0.54) | RAB9ASMN1; SMN2NPC1HPGDCYP1A2 | |
| SCHEMBL3532253 | 0.79 | ATR (0.40) | RAB9ANPC1LMNAPOLBKMT2A | |
| SCHEMBL11522339 | 0.78 | EPHX1 (0.51) | RAB9ASMN1; SMN2NPC1HPGDCYP1A2 | |
| SCHEMBL7554895 | 0.75 | SMN1; SMN2 (0.51) | RAB9ASMN1; SMN2NPC1HPGDCYP1A2 | |
| SCHEMBL9356536 | 0.72 | MAPK1 (0.63) | RAB9ASMN1; SMN2NPC1HPGDCYP1A2 | |
| SCHEMBL8108517 | 0.72 | PLK1 (0.63) | RAB9ASMN1; SMN2NPC1HPGDCYP1A2 | |
| SCHEMBL11520630 | 0.71 | KDM4E (0.55) | RAB9ASMN1; SMN2NPC1HPGDCYP1A2 | |
| SCHEMBL6100315 | 0.70 | L3MBTL1 (0.47) | RAB9ASMN1; SMN2NPC1HPGDCYP1A2 | |
| SCHEMBL4852614 | 0.69 | NLRP3 (0.63) | RAB9ASMN1; SMN2NPC1HPGDCYP1A2 | |
| SCHEMBL3840134 | 0.69 | SMN1; SMN2 (0.60) | RAB9ASMN1; SMN2NPC1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670768-B1 | COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA | LILLY CO ELI (US) | 2009-09-09 | — | — | EP | disclosed |