Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.64 |
| ▸ | XDH | P47989 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BCL6 | P41182 | 1/20 | 0.44 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3173442 | 0.85 | XDH (0.60) | VCAM1XDHLMNAALDH1A1GAA | |
| SCHEMBL16954097 | 0.83 | VCAM1 (0.47) | VCAM1XDHLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL73860 | 0.82 | VCAM1 (0.70) | VCAM1XDHLMNAALDH1A1GAA | |
| Fluoride SCHEMBL28259583 | 0.81 | VCAM1 (0.68) | VCAM1XDHLMNAALDH1A1GAA | |
| SCHEMBL698847 | 0.79 | VCAM1 (0.66) | VCAM1XDHLMNAALDH1A1GAA | |
| SCHEMBL689735 | 0.79 | VCAM1 (0.66) | VCAM1XDHLMNAALDH1A1GAA | |
| SCHEMBL10880668 | 0.78 | VCAM1 (0.64) | VCAM1XDHLMNAALDH1A1GAA | |
| SCHEMBL594390 | 0.78 | VCAM1 (0.64) | VCAM1XDHLMNAALDH1A1GAA | |
| SCHEMBL892830 | 0.78 | VCAM1 (1.00) | VCAM1XDHLMNAALDH1A1GAA | |
| SCHEMBL1343971 | 0.78 | VCAM1 (0.64) | VCAM1XDHLMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230144211-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | BYONDIS B.V. (NL) | 2023-05-11 | — | — | US | disclosed |
| WO-2016160051-A1 | MONOAZO DYES WITH CYCLIC AMINE AS FLUORESCENCE QUENCHERS | ENZO BIOCHEM, INC. (US) | 2016-10-06 | — | — | WO | disclosed |
| EP-1275630-B1 | PROCESS FOR PRODUCING SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS INC (JP) | 2009-10-07 | — | — | EP | disclosed |
| US-20070265451-A1 | Process for the preparation of oxazolidinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2007-11-15 | — | — | US | disclosed |
| EP-1275630-A1 | PROCESS FOR PRODUCING SUBSTITUTED AROMATIC COMPOUND | Mitsui Chemicals, Inc. (JP) | 2003-01-15 | — | — | EP | disclosed |
| US-20020161227-A1 | PROCESS FOR PREPARATION OF SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2002-10-31 | — | — | US | disclosed |
| US-6469224-B1 | REACTING A PHOSPHAZENIUM COMPOUND WITH A HALOGENATED AROMATIC COMPOUNDS, ESPECIALLY CHLORINATED AROMATIC COMPOUNDS | MITSUI CHEMICALS, INC. (JP) | 2002-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265451-A1 | Process for the preparation of oxazolidinones and method of use thereof | OXA1L, OTC, ODC1 | VCAM1 4309/4885XDH 196/4885LMNA 2973/4885 |
| US-20230144211-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | DHFR, FOLR1, MTHFD2 | VCAM1 787/4885XDH 2158/4885LMNA 4482/4885 |
| US-20020161227-A1 | PROCESS FOR PREPARATION OF SUBSTITUTED AROMATIC COMPOUND | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, AFF1, PAH | VCAM1 3204/4885XDH 396/4885LMNA 4102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.