Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 5/20 | 0.41 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15560244 | 0.90 | MAPT (0.48) | MAPTLMNATP53KMT2ASMN1; SMN2 | |
| SCHEMBL22471605 | 0.89 | OPRK1 (0.41) | MAPTLMNATP53KMT2ASMN1; SMN2 | |
| SCHEMBL30898612 | 0.89 | OPRK1 (0.41) | MAPTLMNATP53KMT2ASMN1; SMN2 | |
| SCHEMBL30954712 | 0.87 | KCNK2 (0.47) | MAPTLMNATP53KMT2ASMN1; SMN2 | |
| SCHEMBL30954723 | 0.87 | OPRM1 (0.46) | MAPTLMNATP53KMT2ASMN1; SMN2 | |
| SCHEMBL17584768 | 0.85 | MAPT (0.41) | MAPTLMNATP53KMT2ASMN1; SMN2 | |
| SCHEMBL13480017 | 0.84 | OPRM1 (0.56) | MAPTLMNAKMT2AALDH1A1OPRM1 | |
| SCHEMBL17584777 | 0.84 | OPRM1 (0.47) | MAPTLMNATP53KMT2ASMN1; SMN2 | |
| SCHEMBL25357037 | 0.83 | POLB (0.52) | KMT2AALDH1A1OPRM1OPRL1OPRK1 | |
| SCHEMBL5320118 | 0.83 | OPRM1 (0.44) | MAPTLMNAOPRM1OPRL1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260008760-A1 | DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF | INSMED INCORPORATED | 2026-01-08 | — | — | US | disclosed |
| US-20170073352-A1 | NOVEL SUBSTITUTED SPIROCYCLES | BOEHRINGER INGELHEIM INT (DE) | 2017-03-16 | — | — | US | disclosed |
| US-9540373-B2 | Substituted spirocycles | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-01-10 | — | — | US | disclosed |
| EP-2097376-A2 | SPIRO-PIPERIDINE DERIVATIVES | F. Hoffmann-Roche AG (CH) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008077810-A2 | SPIRO-PIPERIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260008760-A1 | DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF | DPP9, DPP7, DPP4 | MAPT 4670/4885LMNA 3945/4885TP53 4740/4885 |
| US-20170073352-A1 | NOVEL SUBSTITUTED SPIROCYCLES | CTSC, CTSE, CTSS | MAPT 4687/4885LMNA 596/4885TP53 3028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.