Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3842038 | 0.83 | GABRA1 (0.39) | HSD17B10CYP1A2SLC22A6KDM4E | |
| SCHEMBL3840990 | 0.80 | CYP1A2 (0.54) | HSD17B10CYP1A2KDM4E | |
| SCHEMBL3840526 | 0.79 | HSD17B10 (0.38) | HSD17B10CYP1A2SLC22A6KDM4E | |
| SCHEMBL5245809 | 0.75 | GPR84 (0.33) | — | |
| SCHEMBL10366863 | 0.70 | KDM4E (0.37) | HSD17B10CYP1A2SLC22A6KDM4E | |
| SCHEMBL3836798 | 0.70 | SMN1; SMN2 (0.35) | HSD17B10CYP1A2KDM4E | |
| SCHEMBL15515691 | 0.68 | NCEH1 (0.36) | KDM4E | |
| SCHEMBL7424390 | 0.67 | CYP2A6 (0.44) | HSD17B10KDM4E | |
| SCHEMBL3840439 | 0.66 | CYP1A2 (0.36) | CYP1A2KDM4E | |
| SCHEMBL3840588 | 0.66 | CYP1A2 (0.33) | HSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833830-B1 | QUINOLINE DERIVATIVE, USE AND PRODUCTION THEREOF, AND DRUG CONTAINING THE SAME | BAYER SCHERING PHARMA AG (DE) | 2009-10-14 | — | — | EP | disclosed |