Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3840992 | 0.83 | HSD17B10 (0.35) | HSD17B10KDM4ECYP1A2SLC22A6 | |
| SCHEMBL3837986 | 0.82 | KMT2A (0.41) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL5665566 | 0.81 | GABRA1 (0.54) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL3839419 | 0.76 | MEN1 (0.37) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL3840990 | 0.71 | CYP1A2 (0.54) | MEN1KMT2AHSD17B10ALDH1A1HPGD | |
| SCHEMBL7219604 | 0.71 | NQO2 (0.41) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL3837988 | 0.70 | HSD17B10 (0.39) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL3377517 | 0.68 | ALOX5 (0.36) | MEN1KMT2AALDH1A1TYMSCUL4A | |
| SCHEMBL2186757 | 0.66 | SLC22A6 (0.65) | GABRA1GABRB2MEN1KMT2AALDH1A1 | |
| SCHEMBL3840526 | 0.64 | HSD17B10 (0.38) | MEN1KMT2AHSD17B10ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833830-B1 | QUINOLINE DERIVATIVE, USE AND PRODUCTION THEREOF, AND DRUG CONTAINING THE SAME | BAYER SCHERING PHARMA AG (DE) | 2009-10-14 | — | — | EP | disclosed |