Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 4/20 | 0.33 |
| ▸ | DDO | Q99489 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.31 |
| ▸ | CDC25C | P30307 | 1/20 | 0.31 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.30 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.30 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3843000 | 0.81 | GRIN1 (0.39) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL3846952 | 0.81 | TAAR1 (0.36) | KDM4E | |
| SCHEMBL3839869 | 0.80 | DAO (0.56) | KDM4EDAODDOPARP1 | |
| SCHEMBL3843996 | 0.75 | DAO (0.55) | KDM4EDAODDOPARP1 | |
| SCHEMBL4425807 | 0.75 | GPR17 (0.52) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8873562 | 0.70 | DAO (0.51) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL5047640 | 0.70 | MPO (0.36) | KDM4ECNR1PARP1 | |
| SCHEMBL4279370 | 0.69 | CYP2A6 (0.40) | KDM4ECNR1 | |
| SCHEMBL4430524 | 0.69 | LMNA (0.43) | KDM4EGPR17 | |
| SCHEMBL8873411 | 0.68 | KDM4E (0.46) | KDM4EDAODDOPARP1CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044077-A1 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES | Glaxo Group Limited (GB) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008009700-A1 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES | GLAXO GROUP LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |