SCHEMBL3842597

SCHEMBL3842597

CC(C)(C)[Si](C)(C)OCCN1C=C(C(=O)O)CCC1

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4509275 0.88 LMNA (0.33) DUT
SCHEMBL3840279 0.73 OAT (0.37)
SCHEMBL3842966 0.72 KMT2A (0.51)
SCHEMBL3838167 0.71 KDM5A (0.36)
SCHEMBL3837798 0.69 KMT2A (0.50)
SCHEMBL21389245 0.68 KMT2A (0.42) DUT
SCHEMBL20305802 0.68 SMN1; SMN2 (0.44)
SCHEMBL24420592 0.67 L3MBTL1 (0.57) DUT
SCHEMBL30483357 0.66 SMN1; SMN2 (0.41)
SCHEMBL3838127 0.65 OAT (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1931341-B1 1H-INDOLE-PYRIDINECARBOXAMIDE AND 1H-INDOLE-PIPERIDINECARBOXAMIDE DERIVATIVES AND THEIR USE AS TYROSINE HYDROXYLASE INDUCERS SERVIER LAB (FR) 2009-11-04 EP disclosed