Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.61 |
| ▸ | FABP3 | P05413 | 1/20 | 0.51 |
| ▸ | FABP4 | P15090 | 1/20 | 0.51 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.51 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10984209 | 0.85 | HNF4A (0.58) | HNF4AFABP3FABP4FABP5BCAT2 | |
| SCHEMBL8368463 | 0.85 | HNF4A (0.58) | HNF4AFABP3FABP4FABP5BCAT2 | |
| SCHEMBL10676967 | 0.85 | HNF4A (0.49) | HNF4AFABP3FABP4FABP5BCAT2 | |
| SCHEMBL8415183 | 0.85 | HNF4A (0.58) | HNF4AFABP3FABP4FABP5BCAT2 | |
| SCHEMBL8477925 | 0.83 | ALDH1A1 (0.55) | HNF4AALDH1A1ALOX15FOLH1MAPT | |
| SCHEMBL7407371 | 0.81 | HNF4A (0.73) | HNF4AFABP3FABP4FABP5BCAT2 | |
| SCHEMBL6278249 | 0.81 | HNF4A (0.53) | HNF4AFABP3FABP4FABP5BCAT2 | |
| SCHEMBL29017085 | 0.81 | SCN1A (0.47) | HNF4AFABP3FABP4FABP5BCAT2 | |
| SCHEMBL27319579 | 0.80 | HNF4A (0.56) | HNF4AFABP3FABP4FABP5BCAT2 | |
| SCHEMBL36146 | 0.80 | HNF4A (0.66) | HNF4AFABP3FABP4FABP5BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906684-B2 | Antioxidants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-03-15 | — | — | US | disclosed |
| US-20090246158-A1 | ANTIOXIDANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090246158-A1 | ANTIOXIDANTS | LPO, GPX1, GPX4 | HNF4A 3956/4885FABP3 884/4885FABP4 723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.