Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.58 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.52 |
| ▸ | FABP3 | P05413 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27787423 | 0.88 | BCAT2 (0.65) | HNF4ABCAT2DPP4ALDH1A1FOLH1 | |
| SCHEMBL3843396 | 0.85 | HNF4A (0.61) | HNF4ABCAT2FABP3FABP4FABP5 | |
| SCHEMBL27669069 | 0.82 | HMGB1 (0.55) | MYCALDH1A1KDM4EALOX15MAPT | |
| SCHEMBL27950068 | 0.82 | CHRNB2 (0.48) | HNF4ABCAT2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL8415183 | 0.82 | HNF4A (0.58) | HNF4ABCAT2FABP3FABP4FABP5 | |
| SCHEMBL10984209 | 0.82 | HNF4A (0.58) | HNF4ABCAT2FABP3FABP4FABP5 | |
| SCHEMBL27670029 | 0.80 | DPP4 (0.60) | DPP4ALDH1A1HSD17B10 | |
| SCHEMBL3629995 | 0.79 | LTB4R2 (0.57) | HNF4ABCAT2MYCFOLH1 | |
| SCHEMBL7407371 | 0.78 | HNF4A (0.73) | HNF4ABCAT2FABP3FABP4FABP5 | |
| Hydrogen Sulfide SCHEMBL27639876 | 0.78 | DPP4 (0.58) | DPP4ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794789-A4 | INHIBITORS OF PRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 1999-05-26 | — | — | EP | claimed |
| EP-0794789-A1 | INHIBITORS OF PRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1997-09-17 | — | — | EP | claimed |
| WO-1996021456-A1 | INHIBITORS OF PRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1996-07-18 | — | — | WO | claimed |
| CN-102203067-B | Hedgehog pathway modulators | IRM LLC | 2014-01-15 | — | — | CN | disclosed |