SCHEMBL3844580

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3846460	0.92	ADRA1B (0.50)	SLC6A4SLC6A2DRD2DRD3HTR1A
	SCHEMBL3851537	0.90	SLC6A2 (0.45)	SLC6A4SLC6A2DRD2DRD3DRD4
	SCHEMBL3851245	0.89	ALDH1A1 (0.55)	DRD2DRD3HTR1AADRA1AADRA1D
	SCHEMBL3849328	0.89	DRD2 (0.45)	SLC6A4SLC6A2DRD2DRD3DRD1
	SCHEMBL3853707	0.88	DRD2 (0.48)	SLC6A4DRD2DRD3HTR1AADRA2A
	SCHEMBL3854012	0.86	DRD2 (0.57)	SLC6A4DRD2DRD3HTR1AADRA2A
	SCHEMBL3849464	0.86	FFAR4 (0.51)	DRD2HTR1ADRD4ADRA1AADRA1D
	SCHEMBL3845174	0.86	DRD2 (0.59)	SLC6A4DRD2DRD3HTR1AADRA2A
	SCHEMBL3844427	0.85	DRD2 (0.57)	SLC6A4SLC6A2DRD2DRD3HTR1A
	SCHEMBL3845719	0.84	FFAR4 (0.48)	DRD2DRD3HTR1AADRA2ADRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.