SCHEMBL3845207

SCHEMBL3845207

C=CC(=O)CCCCCCCCCCNCCS(=O)(=O)O

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 3/20 0.36
HDAC6 Q9UBN7 1/20 0.33
EPHX2 P34913 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
FAAH O00519 1/20 0.31
HDAC3 O15379 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
NCOR2 Q9Y618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50402 0.81 APP (0.39) EPHX2ALDH1A1TSHRSMN1; SMN2
SCHEMBL5707749 0.79 APP (0.41) EPHX2ALDH1A1TSHRSMN1; SMN2
SCHEMBL79344 0.78 ALDH1A1 (0.33) EPHX2ALDH1A1TSHR
SCHEMBL7859407 0.77 APP (0.39) EPHX2ALDH1A1TSHRSMN1; SMN2
SCHEMBL563191 0.75 ALDH1A1 (0.40) ALDH1A1TSHR
SCHEMBL14505532 0.75 FAAH (0.55) PAOXEPHX2ALDH1A1FAAH
SCHEMBL8513206 0.74 APP (0.42) PAOXALDH1A1TSHR
SCHEMBL23631357 0.74 TSHR (0.48) HDAC6ALDH1A1TSHRSMN1; SMN2FAAH
SCHEMBL22492168 0.74 TSHR (0.48) HDAC6ALDH1A1TSHRSMN1; SMN2FAAH
SCHEMBL2691938 0.74 TSHR (0.48) HDAC6ALDH1A1TSHRSMN1; SMN2FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2024476-B1 COMPOSITIONS COMPRISING LOW-DP POLYMERIZED SURFACTANTS AND METHODS OF USE THEREOF JOHNSON & JOHNSON CONSUMER INC (US) 2017-11-15 EP disclosed
EP-2021447-B1 COMPOSITIONS COMPRISING LOW-DP POLYMERIZED SURFACTANTS AND METHODS OF USE THEREOF JOHNSON & JOHNSON CONSUMER INC (US) 2017-09-13 EP disclosed
EP-2021448-B1 COMPOSITIONS COMPRISING LOW-DP POLYMERIZED SURFACTANTS AND METHODS OF USE THEREOF JOHNSON & JOHNSON CONSUMER INC (US) 2017-09-13 EP disclosed
EP-2024476-A2 COMPOSITIONS COMPRISING LOW-DP POLYMERIZED SURFACTANTS AND METHODS OF USE THEREOF Johnson & Johnson Consumer Companies, Inc. (US) 2009-02-18 EP disclosed
EP-2021447-A1 COMPOSITIONS COMPRISING LOW-DP POLYMERIZED SURFACTANTS AND METHODS OF USE THEREOF JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2009-02-11 EP disclosed
EP-2021448-A2 COMPOSITIONS COMPRISING LOW-DP POLYMERIZED SURFACTANTS AND METHODS OF USE THEREOF Johnson & Johnson Consumer Companies, Inc. (US) 2009-02-11 EP disclosed
US-7446087-B2 Compositions comprising low-DP polymerized surfactants and methods of use thereof JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2008-11-04 US disclosed
US-7446088-B2 Compositions comprising low-DP polymerized surfactants and methods of use thereof JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2008-11-04 US disclosed
US-7417020-B2 low-irritation; for treating the skin, hair, or vaginal region JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2008-08-26 US disclosed
WO-2007130236-A2 COMPOSITIONS COMPRISING LOW-DP POLYMERIZED SURFACTANTS AND METHODS OF USE THEREOF JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2007-11-15 WO disclosed
WO-2007130238-A1 COMPOSITIONS COMPRISING LOW-DP POLYMERIZED SURFACTANTS AND METHODS OF USE THEREOF JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2007-11-15 WO disclosed
WO-2007130237-A2 COMPOSITIONS COMPRISING LOW-DP POLYMERIZED SURFACTANTS AND METHODS OF USE THEREOF JOHNSON & JOHNSON CONSUMER, COMPANIES, INC. (US) 2007-11-15 WO disclosed
US-20070259798-A1 Compositions comprising low-DP polymerized surfactants and methods of use thereof JOHNSON & JOHNSON CONSUMER INC. 2007-11-08 US disclosed
US-20070259797-A1 Compositions comprising low-DP polymerized surfactants and methods of use thereof JOHNSON & JOHNSON CONSUMER INC. 2007-11-08 US disclosed
US-20070259796-A1 Compositions comprising low-DP polymerized surfactants and methods of use thereof JOHNSON & JOHNSON CONSUMER INC. 2007-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070259796-A1 Compositions comprising low-DP polymerized surfactants and methods of use thereof DSG1, DSP, CUTA PAOX 373/4885HDAC6 3504/4885EPHX2 351/4885
US-20070259797-A1 Compositions comprising low-DP polymerized surfactants and methods of use thereof DSG1, DSP, CUTA PAOX 373/4885HDAC6 3504/4885EPHX2 351/4885
US-20070259798-A1 Compositions comprising low-DP polymerized surfactants and methods of use thereof DSG1, DSP, CUTA PAOX 373/4885HDAC6 3504/4885EPHX2 351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.