Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | IDH2 | P48735 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3846891 | 0.80 | IDH2 (0.51) | POLBIDH2FABP4 | |
| SCHEMBL16098691 | 0.80 | ITGB3 (0.48) | MAPTKMT2AIDH2 | |
| SCHEMBL16098694 | 0.80 | ITGB3 (0.48) | MAPTKMT2AIDH2 | |
| SCHEMBL4593633 | 0.73 | MAPT (0.77) | MAPTKMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL28504510 | 0.71 | MAPT (0.68) | MAPTKMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL3830640 | 0.70 | CNR1 (0.48) | POLBIDH2FABP4FABP5 | |
| SCHEMBL10304350 | 0.70 | RAB9A (0.58) | MAPTKMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL4299301 | 0.68 | MAPT (0.59) | MAPTKMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL10596224 | 0.66 | MAPT (0.69) | MAPTKMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL4307428 | 0.66 | MAPT (0.57) | MAPTKMT2AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164104-B | Urea derivative and its purposes as fatty acid binding protein (FABP) inhibitor | 豪夫迈·罗氏有限公司 | 2019-04-12 | — | — | CN | claimed |
| CN-105164104-B | Urea derivative and its purposes as fatty acid binding protein (FABP) inhibitor | 豪夫迈·罗氏有限公司 | 2019-04-12 | — | — | CN | disclosed |