SCHEMBL3847282

SCHEMBL3847282

C=CCN1C(=O)C2C=CCCC2C1=O

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
CASP3 P42574 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
MAPT P10636 1/20 0.33
CYP19A1 P11511 1/20 0.33
POLB P06746 2/20 0.33
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
CNR1 P21554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6256506 0.82
SCHEMBL10967255 0.79 ALDH1A1 (0.31) ALDH1A1
SCHEMBL21461267 0.76 ALDH1A1 (0.32) ALDH1A1MEN1KMT2A
SCHEMBL15184112 0.76 ALDH1A1 (0.41) ALDH1A1MAPTMEN1KMT2A
SCHEMBL8149048 0.76 ALDH1A1 (0.41) ALDH1A1MAPTMEN1KMT2A
SCHEMBL10625294 0.76
SCHEMBL9383280 0.75 MAOA (0.33) CYP19A1
SCHEMBL11818302 0.75 SMN1; SMN2 (0.47) ALDH1A1L3MBTL1MAPTMEN1KMT2A
SCHEMBL3956791 0.74 ALDH1A1 (0.49) ALDH1A1CASP3L3MBTL1MAPTPOLB
SCHEMBL729399 0.74 ALDH1A1 (0.49) ALDH1A1CASP3L3MBTL1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100469817-C Methods for the preparation of poly(etherimides)s GEN ELECTRIC (US) 2009-03-18 CN claimed
CN-1314676-C Preparation of substituted phthalic anhydrides and substituted phthalimides GEN ELECTRIC (US) 2007-05-09 CN claimed
EP-1461329-B1 PREPARATION OF SUBSTITUTED PHTHALIC ANHYDRIDES AND SUBSTITUTED PHTHALIMIDES GEN ELECTRIC (US) 2005-05-25 EP claimed
CN-1617866-A Preparation of substituted phthalic anhydrides and substituted phthalimides GEN ELECTRIC (US) 2005-05-18 CN claimed
CN-1615331-A Methods for the preparation of poly(etherimides)s GEN ELECTRIC (US) 2005-05-11 CN claimed
US-11773207-B2 Thiol compound, method for synthesizing same, and uses for said thiol compound SHIKOKU CHEMICALS CORPORATION (JP) 2023-10-03 US disclosed
US-20220112330-A1 THIOL COMPOUND, METHOD FOR SYNTHESIZING SAME, AND USES FOR SAID THIOL COMPOUND SHIKOKU CHEMICALS CORPORATION (JP) 2022-04-14 US disclosed
CN-113272274-A Thiol compound, synthesis method thereof and application of thiol compound 四国化成工业株式会社 2021-08-17 CN disclosed
WO-2020145111-A1 THIOL COMPOUND, METHOD FOR SYNTHESIZING SAME, AND USES FOR SAID THIOL COMPOUND 四国化成工業株式会社 2020-07-16 WO disclosed
CN-100469817-C Methods for the preparation of poly(etherimides)s GEN ELECTRIC (US) 2009-03-18 CN disclosed
EP-1828267-A4 FLAME RETARDANT EXPANDED POLYSTYRENE FOAM COMPOSITIONS ALBEMARLE CORP (US) 2009-01-14 EP disclosed
US-20080096992-A1 Flame Retardant Extruded Polystyrene Foam Compositions ALBEMARLE CORPORATION (US) 2008-04-24 US disclosed
CN-1314676-C Preparation of substituted phthalic anhydrides and substituted phthalimides GEN ELECTRIC (US) 2007-05-09 CN disclosed
WO-2006071213-A1 FLAME RETARDANT EXPANDED POLYSTYRENE FOAM COMPOSITIONS ALBEMARLE CORPORATION (US) 2006-07-06 WO disclosed
WO-2006071214-A1 FLAME RETARDANT EXTRUDED POLYSTYRENE FOAM COMPOSITIONS ALBEMARLE CORPORATION (US) 2006-07-06 WO disclosed
EP-1461329-B1 PREPARATION OF SUBSTITUTED PHTHALIC ANHYDRIDES AND SUBSTITUTED PHTHALIMIDES GEN ELECTRIC (US) 2005-05-25 EP disclosed
CN-1617866-A Preparation of substituted phthalic anhydrides and substituted phthalimides GEN ELECTRIC (US) 2005-05-18 CN disclosed
CN-1615331-A Methods for the preparation of poly(etherimides)s GEN ELECTRIC (US) 2005-05-11 CN disclosed
EP-1461329-A1 PREPARATION OF SUBSTITUTED PHTHALIC ANHYDRIDES AND SUBSTITUTED PHTHALIMIDES GENERAL ELECTRIC COMPANY (US) 2004-09-29 EP disclosed
WO-2003050103-A1 PREPARATION OF SUBSTITUTED PHTHALIC ANHYDRIDES AND SUBSTITUTED PHTHALIMIDES GENERAL ELECTRIC COMPANY (US) 2003-06-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11773207-B2 Thiol compound, method for synthesizing same, and uses for said thiol compound TST, TMT1A, CTH ALDH1A1 412/4885CASP3 3645/4885L3MBTL1 2932/4885
US-20220112330-A1 THIOL COMPOUND, METHOD FOR SYNTHESIZING SAME, AND USES FOR SAID THIOL COMPOUND TST, TMT1A, CTH ALDH1A1 412/4885CASP3 3645/4885L3MBTL1 2932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.