Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3122471 | 0.83 | ELANE (0.33) | ELANEALDH1A1TSHRPRKCA | |
| SCHEMBL493095 | 0.79 | ALDH1A1 (0.46) | ELANEALDH1A1TSHR | |
| SCHEMBL65267 | 0.78 | ELANE (0.40) | ELANEALDH1A1TSHRPRKCA | |
| SCHEMBL1725969 | 0.78 | ELANE (0.33) | ELANEPRKCA | |
| SCHEMBL11876913 | 0.78 | ELANE (0.33) | ELANEALDH1A1TSHRPRKCA | |
| SCHEMBL30467555 | 0.77 | PRKCA (0.31) | ELANEPRKCA | |
| SCHEMBL4316110 | 0.77 | ALDH1A1 (0.53) | ELANEALDH1A1TSHRPRKCA | |
| SCHEMBL214755 | 0.77 | ALDH1A1 (0.53) | ELANEALDH1A1TSHRPRKCA | |
| SCHEMBL5151400 | 0.76 | ELANE (0.32) | ELANE | |
| SCHEMBL5451160 | 0.76 | ELANE (0.32) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2080765-A1 | Phosphonocephem Derivates, Their Production And Use | Takeda Pharmaceutical Company Limited (JP) | 2009-07-22 | — | — | EP | disclosed |
| EP-1043327-B1 | PHOSPHONOCEPHEM DERIVATIVES, PROCESS FOR THE PREPARATION OF THE SAME, AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2009-04-29 | — | — | EP | disclosed |
| US-6417175-B1 | Phosphonocephem derivatives, process for the preparation of the same, and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-09 | — | — | US | disclosed |
| EP-1043327-A1 | PHOSPHONOCEPHEM DERIVATIVES, PROCESS FOR THE PREPARATION OF THE SAME, AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-10-11 | — | — | EP | disclosed |
| US-5948774-A | EXCELLENT ANTIBACTERIAL ACTIVITIES ON A BROAD RANGE OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA, ESPECIALLY STAPHYLOCOCCUS AUREUS AND METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0828744-A1 | CEPHEM COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996038451-A1 | CEPHEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-05 | — | — | WO | disclosed |
| EP-0733055-A1 | 2-SPIRO(2'-SPIROCYCLOALKYL)CYCLOPROPYL CEPHALOSPORIN SULFONES AS ANTIINFLAMMATORY AND ANTIDEGENERATIVE AGENTS | SYNPHAR LABORATORIES INC. (CA) | 1996-09-25 | — | — | EP | disclosed |
| WO-1996023798-A1 | CEPHEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-08 | — | — | WO | disclosed |
| US-5439904-A | Enzyme inhibitors of human leukocyte elastase; respiratory system disorders; antiarthritic agents | SYNPHAR LABORATORIES, INC. (CA) | 1995-08-08 | — | — | US | disclosed |
| EP-0228061-A2 | Cephem compounds | Takeda Chemical Industries, Ltd. (JP) | 1987-07-08 | — | — | EP | disclosed |
| EP-0225634-A2 | Antibacterial compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-06-16 | — | — | EP | disclosed |
| US-4665065-A | 3-pyrazolo(1,5-aαpyridinium cephem compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| EP-0216385-A2 | Antibacterial compounds | Takeda Chemical Industries, Ltd. (JP) | 1987-04-01 | — | — | EP | disclosed |
| EP-0203271-A2 | Antibacterial compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-12-03 | — | — | EP | disclosed |
| WO-1986005183-A1 | ANTIBACTERIAL COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-09-12 | — | — | WO | disclosed |
| EP-0164113-A2 | 3-pyrazolo(1,5-a)pyridinium cephem compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-12-11 | — | — | EP | disclosed |
| EP-0164122-A2 | Cephem compounds | Takeda Chemical Industries, Ltd. (JP) | 1985-12-11 | — | — | EP | disclosed |
| EP-0160969-A2 | Cephem compounds | Takeda Chemical Industries, Ltd. (JP) | 1985-11-13 | — | — | EP | disclosed |
| EP-0160252-A2 | Antibacterial compounds | Takeda Chemical Industries, Ltd. (JP) | 1985-11-06 | — | — | EP | disclosed |