SCHEMBL3849971

SCHEMBL3849971

C=CC(=O)OC12CC3CC(CC(C3)C1)C2.CC(C)(C)OC(=O)COc1ccc(C=CC=Cc2ccc(O)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.41
RAB9A P51151 2/20 0.41
KMT2A Q03164 2/20 0.41
NPC1 O15118 1/20 0.41
EPHX2 P34913 1/20 0.36
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
XBP1 P17861 1/20 0.34
PTGS2 P35354 2/20 0.34
STAT3 P40763 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ABCG2 Q9UNQ0 3/20 0.33
MAOB P27338 1/20 0.33
ESR1 P03372 3/20 0.33
MIF P14174 1/20 0.32
PSEN1 P49768 1/20 0.32
PSEN2 P49810 1/20 0.32
APH1B Q8WW43 1/20 0.32
NCSTN Q92542 1/20 0.32
APH1A Q96BI3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3843081 0.87 KDM1A (0.39) MEN1KMT2AEPHX2GAAMAPT
SCHEMBL3841430 0.86 MAPT (0.38) MEN1RAB9AKMT2AGAAMAPT
SCHEMBL5446080 0.81 CYP1A2 (0.37) MEN1RAB9AKMT2ANPC1GAA
SCHEMBL5449120 0.81 MAPT (0.40) MEN1RAB9AKMT2AGAAMAPT
SCHEMBL2964490 0.81 MEN1 (0.49) MEN1RAB9AKMT2ANPC1GAA
SCHEMBL5449150 0.80 ESR1 (0.39) KMT2AGAAMAPTXBP1STAT3
SCHEMBL5435451 0.79 AKR1B10 (0.38) MEN1RAB9AKMT2AGAAMAPT
SCHEMBL8045161 0.79 MEN1 (0.39) MEN1RAB9AKMT2ANPC1MAPT
SCHEMBL5450986 0.78 THRB (0.46) KMT2AMAOBESR1
SCHEMBL5455488 0.78 CYP17A1 (0.37) MEN1RAB9AKMT2ANPC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1449833-B1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION WAKO PURE CHEM IND LTD (JP) 2009-09-09 EP disclosed
US-7374857-B2 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2008-05-20 US disclosed
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2005-02-17 US disclosed
EP-1449833-A1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION Wako Pure Chemical Industries, Ltd. (JP) 2004-08-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition ASIC1, GAR1, RER1 MEN1 211/4885RAB9A 396/4885KMT2A 1016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.