SCHEMBL7789586

SCHEMBL7789586

C=CC[SiH](F)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TSHR P16473 2/20 0.33
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL216362 0.76 ALDH1A1 (0.36) ALDH1A1TSHRCYP2C19
SCHEMBL860549 0.76 CYP2C19 (0.36) ALDH1A1TSHRCYP2C19
SCHEMBL8992328 0.73 ALDH1A1 (0.33) ALDH1A1TSHRCYP2C19
SCHEMBL9267683 0.73 CYP1A2 (0.35) ALDH1A1TSHRCYP2C19
SCHEMBL3850181 0.73 ALDH1A1 (0.33) ALDH1A1TSHRCYP2C19
SCHEMBL9256810 0.73 ALDH1A1 (0.33) ALDH1A1TSHRCYP2C19
SCHEMBL1493083 0.73 ALDH1A1 (0.33) ALDH1A1TSHRCYP2C19
SCHEMBL9267676 0.73 ALDH1A1 (0.34) ALDH1A1TSHRCYP2C19
SCHEMBL11316909 0.70 CYP2C19 (0.32) ALDH1A1TSHRCYP2C19
SCHEMBL15302263 0.69 TP53 (0.38) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1124519-C Photomask blanks DU PONT (US) 2003-10-15 CN claimed
EP-0909406-B1 PHOTOMASK BLANKS DU PONT (US) 2001-11-21 EP claimed
US-5876686-A HYBRID COATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-03-02 US claimed
EP-0837901-A1 FLUOROPOLYMER NANOCOMPOSITES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-04-29 EP claimed
US-5726247-A Fluoropolymer nanocomposites E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-03-10 US claimed
WO-1997001508-A1 PROCESS FOR MAKING INORGANIC OXIDE GELS IN FLUOROCARBON SOLVENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-01-16 WO claimed
WO-1997001599-A1 FLUOROPOLYMER NANOCOMPOSITES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-01-16 WO claimed
US-5876686-A HYBRID COATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-03-02 US disclosed
EP-0837901-A1 FLUOROPOLYMER NANOCOMPOSITES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-04-29 EP disclosed
US-5726247-A Fluoropolymer nanocomposites E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-03-10 US disclosed
WO-1997001508-A1 PROCESS FOR MAKING INORGANIC OXIDE GELS IN FLUOROCARBON SOLVENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-01-16 WO disclosed
WO-1997001599-A1 FLUOROPOLYMER NANOCOMPOSITES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-01-16 WO disclosed