Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 2/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13429229 | 0.82 | SMPD1 (0.32) | SMPD1 | |
| SCHEMBL17660397 | 0.72 | RAB9A (0.47) | APOBEC3AAPOBEC3GKDM4EHSD17B10ALOX15 | |
| SCHEMBL7263917 | 0.72 | HSD17B10 (0.42) | APOBEC3AAPOBEC3GKDM4EHSD17B10ALOX15 | |
| SCHEMBL1828616 | 0.71 | — | — | |
| SCHEMBL23635941 | 0.71 | KDM4E (0.39) | APOBEC3AAPOBEC3GKDM4EHSD17B10ALOX15 | |
| SCHEMBL6124859 | 0.69 | — | — | |
| SCHEMBL12705 | 0.66 | — | — | |
| SCHEMBL18141918 | 0.64 | APOBEC3A (0.54) | APOBEC3AAPOBEC3GKDM4EHSD17B10ALOX15 | |
| SCHEMBL265221 | 0.64 | KDM4E (0.36) | APOBEC3AAPOBEC3GKDM4EHSD17B10ALOX15 | |
| Ammonia Solution, Strong SCHEMBL3447928 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576220-B2 | Method of producing 1,2,4-oxadiazole derivatives | RIKKYO GAKUIN (JP) | 2009-08-18 | — | — | US | claimed |
| US-20080086009-A1 | Method of producing 1,2,4-oxadiazole derivatives | RIKKYO GAKUIN (JP) | 2008-04-10 | — | — | US | claimed |
| US-7576220-B2 | Method of producing 1,2,4-oxadiazole derivatives | RIKKYO GAKUIN (JP) | 2009-08-18 | — | — | US | disclosed |
| US-20080086009-A1 | Method of producing 1,2,4-oxadiazole derivatives | RIKKYO GAKUIN (JP) | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080086009-A1 | Method of producing 1,2,4-oxadiazole derivatives | NOS1, NOS2, NOS3 | APOBEC3A 420/4885APOBEC3G 794/4885KDM4E 2292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.