Water

Water

SCHEMBL3852390

O.O.O.[Ru]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL10821743 1.00
Water SCHEMBL8428255 1.00
Water SCHEMBL1072652 1.00
Water SCHEMBL10950177 1.00
Water SCHEMBL4756112 1.00
Water SCHEMBL379838 1.00
Water SCHEMBL6661340 1.00
Water SCHEMBL10939064 1.00
Water SCHEMBL3172620 1.00
Water SCHEMBL27669956 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2580366-B1 PROCESS FOR SUBSTRATE COATING ON ONE OR MORE SIDES THYSSENKRUPP IND SOLUTIONS AG (DE) 2020-05-06 EP claimed
CN-108690005-A The chrysamides B synthetic methods of natural products containing nitro and its diastereoisomer-compound 兰州大学 2018-10-23 CN claimed
EP-1461402-B1 METHOD AND COMPOSITION FOR IMPROVING FUEL COMBUSTION CARROLL ASSOCIATES LLC (US) 2009-05-27 EP claimed
US-4170605-A Synthesis of ethylene glycol from carbon monoxide and hydrogen using a ruthenium complex catalyst and a pyridine base ligand GULF RESEARCH AND DEVELOPMENT COMPANY (US) 1979-10-09 US claimed
CN-113720879-B Preparation method and application of acetone gas-sensitive material and acetone gas sensor 华南师范大学 2023-10-03 CN disclosed
CN-106164028-B Composite metal catalyst composition and the method and apparatus for being used to prepare 1,4 cyclohexane dimethanol using it 乐天化学株式会社 2019-07-26 CN disclosed
CN-108690005-A The chrysamides B synthetic methods of natural products containing nitro and its diastereoisomer-compound 兰州大学 2018-10-23 CN disclosed
CN-106999451-A Dicyclic compound 卡利拉制药公司 2017-08-01 CN disclosed
CN-103080118-B Ruthenium-diamine complexe and the method for producing optically active compound TAKASAGO INTERNATIONAL CORP. (JP) 2016-05-11 CN disclosed
CN-104402930-A Symmetric benzimidazole ruthenium complex and preparation method thereof UNIV KUNMING SCIENCE & TECHNOLOGY 2015-03-11 CN disclosed
US-7358004-B2 Carbon black, electrocatalyst carrier formed from carbon black, and electrocatalyst and electrochemical device using carrier N. E. CHEMCAT CORPORATION (JP) 2008-04-15 US disclosed
CN-1543451-A Receptor modulators activated by peroxizonal proliferators (ppar) 2004-11-03 CN disclosed
EP-0564568-A1 METHOD FOR HYDROGENATING ETHYLENICALLY UNSATURATED ORGANIC COMPOUNDS, AND RUTHENIUM CATALYSERS THEREFOR. ELF AQUITAINE (FR) 1993-10-13 EP disclosed
EP-0332521-B1 PROCESS FOR THE PREPARATION OF CYCLIC SULFATES RHONE-POULENC SANTE (FR) 1992-10-07 EP disclosed
WO-1992012110-A1 METHOD FOR HYDROGENATING ETHYLENICALLY UNSATURATED ORGANIC COMPOUNDS, AND RUTHENIUM CATALYSERS THEREFOR SOCIETE NATIONALE ELF AQUITAINE (FR) 1992-07-23 WO disclosed
EP-0332521-A1 Process for the preparation of cyclic sulfates RHONE-POULENC SANTE (FR) 1989-09-13 EP disclosed
EP-0192587-A1 Process for the hydrogenation of acetic acid RHONE-POULENC CHIMIE DE BASE (FR) 1986-08-27 EP disclosed
US-4243610-A Cobalt-gold promoter for ruthenium hydrogenation catalyst as in hydrogenation of unsaturated dinitriles PHILLIPS PETROLEUM COMPANY (US) 1981-01-06 US disclosed
US-4215019-A Ruthenium-cobalt-gold catalyst for hydrogenation of unsaturated dinitriles PHILLIPS PETROLEUM COMPANY (US) 1980-07-29 US disclosed
US-4170605-A Synthesis of ethylene glycol from carbon monoxide and hydrogen using a ruthenium complex catalyst and a pyridine base ligand GULF RESEARCH AND DEVELOPMENT COMPANY (US) 1979-10-09 US disclosed