Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 5/20 | 0.61 |
| ▸ | PPARG | P37231 | 10/20 | 0.57 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3852753 | 0.90 | PLA2G2A (0.53) | PLA2G2APPARGPLA2G1BMAPTGAA | |
| SCHEMBL3852991 | 0.89 | PLA2G2A (0.54) | PLA2G2APPARG | |
| SCHEMBL3854541 | 0.88 | PLA2G2A (0.67) | PLA2G2APPARGPLA2G1B | |
| SCHEMBL3854740 | 0.83 | TSHR (0.57) | PLA2G2APPARGPLA2G1BMAPTKMT2A | |
| SCHEMBL3853126 | 0.82 | MAPT (0.48) | PLA2G2APPARGPLA2G1BTDP1MAPT | |
| SCHEMBL3854712 | 0.81 | PLA2G2A (0.55) | PLA2G2APPARGTDP1MAPTMEN1 | |
| SCHEMBL3854882 | 0.81 | PLA2G2A (0.49) | PLA2G2APPARGPLA2G1BMEN1KMT2A | |
| SCHEMBL3852008 | 0.80 | ESR1 (0.51) | PLA2G2A | |
| SCHEMBL635012 | 0.80 | PLA2G2A (0.56) | PLA2G2APPARG | |
| SCHEMBL3852304 | 0.80 | PLA2G2A (0.53) | PLA2G2APPARGPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582773-B2 | Substituted phenyl indoles | WYETH (US) | 2009-09-01 | — | — | US | claimed |
| US-20050070592-A1 | Substituted phenyl indoles | WYETH (US) | 2005-03-31 | — | — | US | claimed |
| US-7582773-B2 | Substituted phenyl indoles | WYETH (US) | 2009-09-01 | — | — | US | disclosed |
| US-20050070592-A1 | Substituted phenyl indoles | WYETH (US) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070592-A1 | Substituted phenyl indoles | TPH2, IDO2, AANAT | PLA2G2A 3821/4885PPARG 1741/4885PLA2G1B 3476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.