Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 19/20 | 0.67 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3855935 | 0.91 | PLA2G2A (0.57) | PLA2G2APLA2G1B | |
| SCHEMBL3853074 | 0.88 | PLA2G2A (0.61) | PLA2G2APLA2G1BPPARG | |
| SCHEMBL3852304 | 0.88 | PLA2G2A (0.53) | PLA2G2APLA2G1BPPARG | |
| SCHEMBL3857096 | 0.87 | PPARG (0.57) | PLA2G2APLA2G1BPPARG | |
| SCHEMBL3857137 | 0.85 | PLA2G2A (0.61) | PLA2G2APLA2G1B | |
| SCHEMBL3853281 | 0.83 | PLA2G2A (0.50) | PLA2G2APLA2G1B | |
| SCHEMBL3854952 | 0.82 | PLA2G2A (0.60) | PLA2G2APLA2G1B | |
| SCHEMBL3852991 | 0.82 | PLA2G2A (0.54) | PLA2G2APPARG | |
| SCHEMBL3852177 | 0.81 | PPARG (0.55) | PLA2G2APLA2G1BPPARG | |
| SCHEMBL3854601 | 0.80 | PLA2G2A (0.49) | PLA2G2APLA2G1BPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582773-B2 | Substituted phenyl indoles | WYETH (US) | 2009-09-01 | — | — | US | claimed |
| US-20050070592-A1 | Substituted phenyl indoles | WYETH (US) | 2005-03-31 | — | — | US | claimed |
| US-7582773-B2 | Substituted phenyl indoles | WYETH (US) | 2009-09-01 | — | — | US | disclosed |
| US-20050070592-A1 | Substituted phenyl indoles | WYETH (US) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070592-A1 | Substituted phenyl indoles | TPH2, IDO2, AANAT | PLA2G2A 3821/4885PLA2G1B 3476/4885PPARG 1741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.