SCHEMBL3853620

SCHEMBL3853620

COc1cc(C(=O)Cl)ccc1O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.72
KMT2A Q03164 2/20 0.72
SLC22A6 Q4U2R8 1/20 0.72
SLC22A8 Q8TCC7 1/20 0.72
RAB9A P51151 1/20 0.72
HTT P42858 1/20 0.70
HSD17B2 P37059 1/20 0.60
CYP1A2 P05177 1/20 0.58
HSP90AA1 P07900 1/20 0.58
HSP90AB1 P08238 1/20 0.58
BLM P54132 1/20 0.58
KDM4E B2RXH2 1/20 0.57
POLB P06746 1/20 0.57
HDAC6 Q9UBN7 1/20 0.57
ALDH1A1 P00352 2/20 0.54
GAA P10253 2/20 0.54
HPGD P15428 2/20 0.54
HSD17B10 Q99714 2/20 0.54
MAPT P10636 1/20 0.54
ALOX15 P16050 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14800073 0.85 TUBB4A (0.60) MEN1KMT2ASLC22A6SLC22A8RAB9A
SCHEMBL31696789 0.85 TUBB4A (0.60) MEN1KMT2ASLC22A6SLC22A8RAB9A
SCHEMBL184025 0.84 TSHR (0.70) CYP1A2POLBALDH1A1GAAHPGD
SCHEMBL29521706 0.84 TSHR (0.70) CYP1A2POLBALDH1A1GAAHPGD
SCHEMBL15814046 0.84 SLC22A6 (1.00) MEN1KMT2ASLC22A6SLC22A8RAB9A
SCHEMBL15289000 0.84 MEN1 (1.00) MEN1KMT2ASLC22A6SLC22A8RAB9A
SCHEMBL29532454 0.84 MEN1 (1.00) MEN1KMT2ASLC22A6SLC22A8RAB9A
Vanillic Acid SCHEMBL26179 0.82 HTT (1.00) MEN1KMT2ASLC22A6SLC22A8RAB9A
Vanillic Acid SCHEMBL9711598 0.82 HTT (1.00) MEN1KMT2ASLC22A6SLC22A8RAB9A
Apocynin SCHEMBL109514 0.82 MEN1 (0.75) MEN1KMT2ASLC22A6SLC22A8RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260102359-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION ERESINA LLC (US) 2026-04-16 US claimed
EP-4593859-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION Eresina, LLC (US) 2025-08-06 EP claimed
WO-2024073011-A1 TOPICAL COMPOSITIONS AND METHODS FOR THE TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION ERESINA, LLC (US) 2024-04-04 WO claimed
WO-2024073013-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION ERESINA, LLC (US) 2024-04-04 WO claimed
EP-2835634-B1 Methods and devices for calibrating the mobility axis of an ion mobility spectrum BRUKER DALTONIK GMBH (DE) 2017-10-04 EP claimed
EP-3109226-A1 PROCESS FOR PREPARING VANILLIN BASF SE (DE) 2016-12-28 EP claimed
US-9153423-B2 Methods and devices for calibrating the mobility axis of an ion mobility spectrum BRUKER OPTICS GMBH & CO. KG (DE) 2015-10-06 US claimed
US-20150129760-A1 METHODS AND DEVICES FOR CALIBRATING THE MOBILITY AXIS OF AN ION MOBILITY SPECTRUM BRUKER OPTICS GMBH & CO. KG (DE) 2015-05-14 US claimed
EP-2835634-A1 Methods and devices for calibrating the mobility axis of an ion mobility spectrum Bruker Daltonik GmbH (DE) 2015-02-11 EP claimed
EP-2670501-A1 REMOVING COMPOUNDS FROM WINE Constellation Brands U.S. Operations, Inc. (US) 2013-12-11 EP claimed
WO-2012106265-A1 REMOVING COMPOUNDS FROM WINE CONSTELLATION WINES U.S., INC. (US) 2012-08-09 WO claimed
US-20120196024-A1 REMOVING COMPOUNDS FROM WINE CONSTELLATION WINES U.S., INC. (US) 2012-08-02 US claimed
US-3951914-A Process for preparing poly(1,4-benzamide) in cyclic sulfone media E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-04-20 US claimed
US-20260102359-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION ERESINA LLC (US) 2026-04-16 US disclosed
EP-4593859-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION Eresina, LLC (US) 2025-08-06 EP disclosed
US-20240300930-A1 NOVEL PROCESS FOR THE PREPARATION OF 2,5-DICHLORO-3-(5-(3,4-DIHYDROXY-5-NITROPHENYL)-1,2,4-OXADIAZOL-3-YL)-4,6-DIMETHYLPYRIDINE-1-OXIDE MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) 2024-09-12 US disclosed
US-3991016-A Poly(1,4-benzamide) copolymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-11-09 US disclosed
US-3965093-A 6-Arylthio penicillanic acid and derivatives thereof E. R. SQUIBB & SONS, INC. (US) 1976-06-22 US disclosed
US-3954744-A ANTIBACTERIAL E. R. SQUIBB & SONS, INC. (US) 1976-05-04 US disclosed
US-3951914-A Process for preparing poly(1,4-benzamide) in cyclic sulfone media E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240300930-A1 NOVEL PROCESS FOR THE PREPARATION OF 2,5-DICHLORO-3-(5-(3,4-DIHYDROXY-5-NITROPHENYL)-1,2,4-OXADIAZOL-3-YL)-4,6-DIMETHYLPYRIDINE-1-OXIDE NOX4, DDT, QDPR MEN1 2741/4885KMT2A 1854/4885SLC22A6 4495/4885
US-20260102359-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION COL2A1, COLGALT1, PLOD3 MEN1 4053/4885KMT2A 1308/4885SLC22A6 2277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.