Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.70 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 2/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.57 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.57 |
| ▸ | NSD2 | O96028 | 2/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1954496 | 0.94 | CYP19A1 (0.80) | CYP19A1KEAP1LMNASMN1; SMN2CA12 | |
| SCHEMBL28003786 | 0.84 | CYP19A1 (0.67) | CYP19A1LMNASMN1; SMN2CA12CA9 | |
| SCHEMBL20946410 | 0.84 | CYP19A1 (0.71) | CYP19A1KEAP1CA12CA9CA1 | |
| SCHEMBL7169118 | 0.84 | CYP19A1 (0.67) | CYP19A1KEAP1LMNASMN1; SMN2CA12 | |
| SCHEMBL14196598 | 0.84 | CA2 (0.68) | CYP19A1CA12CA9CA1CA2 | |
| SCHEMBL12010890 | 0.84 | NAMPT (0.72) | CYP19A1LMNASMN1; SMN2CA12CA9 | |
| SCHEMBL12982899 | 0.84 | KEAP1 (0.69) | KEAP1LMNASMN1; SMN2CA12CA9 | |
| SCHEMBL30927212 | 0.83 | CYP19A1 (0.74) | CYP19A1KEAP1LMNASMN1; SMN2CA12 | |
| SCHEMBL6567375 | 0.83 | CYP19A1 (0.74) | CYP19A1KEAP1LMNASMN1; SMN2CA12 | |
| SCHEMBL407414 | 0.82 | KEAP1 (1.00) | KEAP1LMNASMN1; SMN2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-103588697-B | Disubstituted benzenes sulfamide compound of one class 2,5 and its production and use | 中国科学院上海药物研究所 | 2017-09-15 | — | — | CN | claimed |
| CN-103588697-B | Disubstituted benzenes sulfamide compound of one class 2,5 and its production and use | 中国科学院上海药物研究所 | 2017-09-15 | — | — | CN | disclosed |
| WO-2009152082-A1 | HYDROXYPHENYLSULFONAMIDES AS ANTIAPOPTOTIC BCL INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-12-17 | — | — | WO | disclosed |
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | WYETH | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | HSD11B1, HSD11B2, HSD3B1 | CYP19A1 27/4885KEAP1 921/4885LMNA 3336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.