SCHEMBL3854433

SCHEMBL3854433

O=C(O)C(=C(F)c1cc(F)c(F)c(F)c1F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CES2 O00748 3/20 0.33
CES1 P23141 3/20 0.33
CRBN Q96SW2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11173466 0.78 CES2 (0.38) KEAP1NFE2L2SMN1; SMN2TDP1CES2
SCHEMBL466255 0.74 ALDH1A1 (0.50) TDP1CES2CES1
Fluoride SCHEMBL28471026 0.72 CES2 (0.46) KEAP1NFE2L2SMN1; SMN2TDP1CES2
SCHEMBL4851418 0.72 CES2 (0.46) KEAP1NFE2L2SMN1; SMN2TDP1CES2
Fluoride SCHEMBL28471027 0.71 KEAP1 (0.47) KEAP1NFE2L2SMN1; SMN2TDP1CES2
SCHEMBL29816825 0.71 KEAP1 (0.47) KEAP1NFE2L2SMN1; SMN2TDP1CES2
Fluoride SCHEMBL6445071 0.71 KEAP1 (0.47) KEAP1NFE2L2SMN1; SMN2TDP1CES2
SCHEMBL345016 0.71 ALDH1A1 (0.48) KEAP1NFE2L2SMN1; SMN2TDP1CES2
SCHEMBL503374 0.71 KEAP1 (0.47) KEAP1NFE2L2SMN1; SMN2TDP1CES2
Trifluoroacetic Acid SCHEMBL27519545 0.71 CA1 (0.44) SMN1; SMN2TDP1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8361663-B2 Porous carbon structure, method for preparing same, electrode catalyst for fuel cell, and electrode and membrane-electrode assembly including same SAMSUNG SDI CO., LTD. (KR) 2013-01-29 US disclosed
US-20090136808-A1 Porous carbon structure, method for preparing same, electrode catalyst for fuel cell, and electrode and membrane-electrode assembly including same SAMSUNG SDI CO., LTD., A CORPORATION CHARTERED IN AND EXISTING UNDER THE LAWS OF THE REPUBLIC OF KOREA (KR) 2009-05-28 US disclosed