SCHEMBL466255

SCHEMBL466255

O=C(O)C(=C(F)c1ccccc1F)C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
ALOX15 P16050 1/20 0.50
CES1 P23141 4/20 0.48
CES2 O00748 3/20 0.48
PTPN1 P18031 1/20 0.46
ERCC5 P28715 1/20 0.46
FEN1 P39748 1/20 0.46
GAA P10253 1/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
TDP1 Q9NUW8 1/20 0.41
NPC1 O15118 3/20 0.40
HPGD P15428 2/20 0.40
MAPT P10636 1/20 0.40
RAB9A P51151 2/20 0.39
ALB P02768 1/20 0.39
TRPV1 Q8NER1 1/20 0.38
LMNA P02545 1/20 0.38
KAT6A Q92794 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4183753 0.77 CES2 (0.56) ALDH1A1ALOX15CES1CES2PTPN1
SCHEMBL6656819 0.77 CES1 (0.54) ALDH1A1ALOX15CES1CES2PTPN1
SCHEMBL3854433 0.74 KEAP1 (0.36) CES1CES2TDP1
Trifluoroacetic Acid SCHEMBL19123998 0.73 CES1 (0.56) ALDH1A1ALOX15CES1CES2PTPN1
SCHEMBL29668746 0.72 CES1 (0.60) ALDH1A1ALOX15CES1CES2PTPN1
SCHEMBL361933 0.72 CES1 (0.60) ALDH1A1ALOX15CES1CES2PTPN1
SCHEMBL29053354 0.71 FAAH (0.41) ALDH1A1CES1GAAKMT2AMAPT
Trifluoroacetic Acid SCHEMBL1788206 0.70 CES2 (0.52) ALDH1A1ALOX15CES1CES2PTPN1
SCHEMBL6002438 0.70 CES2 (0.77) ALDH1A1ALOX15CES1CES2PTPN1
SCHEMBL15180841 0.70 CES2 (0.77) ALDH1A1ALOX15CES1CES2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365765-A1 Articles and Methods for Manufacture of Nanostructure Reinforced Composites NAWA AMERICA INC (US) 2023-11-16 US claimed
EP-4261920-A1 METHOD FOR FLUORINATING A LITHIUM METAL SURFACE Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2023-10-18 EP claimed
US-20220145037-A1 METHODS OF PREPARATION OF OMNIPHOBIC SURFACES NUTECH VENTURES (US) 2022-05-12 US claimed
EP-3102404-B1 METHOD FOR MANUFACTURE OF NANOSTRUCTURE REINFORCED COMPOSITES NAWA AMERICA INC (US) 2021-06-30 EP claimed
EP-3102404-A1 ARTICLES AND METHODS FOR MANUFACTURE OF NANOSTRUCTURE REINFORCED COMPOSITES N12 Technologies, Inc. (US) 2016-12-14 EP claimed
US-20160340482-A1 Articles and Methods for Manufacture of Nanostructure Reinforced Composites N12 TECHNOLOGIES, INC. 2016-11-24 US claimed
EP-2370347-A2 MULTIFUNCTIONAL COMPOSITES BASED ON COATED NANOSTRUCTURES Massachusetts Institute of Technology (US) 2011-10-05 EP claimed
WO-2010120273-A2 MULTIFUNCTIONAL COMPOSITES BASED ON COATED NANOSTRUCTURES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2010-10-21 WO claimed
US-20100255303-A1 MULTIFUNCTIONAL COMPOSITES BASED ON COATED NANOSTRUCTURES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2010-10-07 US claimed
US-6341190-B1 Organic optical components and preparation thereof EPIGEM LIMITED (GB) 2002-01-22 US claimed
EP-0722387-B1 ORGANIC OPTICAL COMPONENTS AND PREPARATION THEREOF EPIGEM LIMITED (GB) 2000-09-06 EP claimed
US-5985084-A Organic optical components and preparation thereof EPIGEM LTD. (GB) 1999-11-16 US claimed
EP-0722387-A1 ORGANIC OPTICAL COMPONENTS AND PREPARATION THEREOF Epigem Limited (GB) 1996-07-24 EP claimed
US-5496675-A Carrier coating and processes XEROX CORPORATION (US) 1996-03-05 US claimed
WO-1995009726-A1 ORGANIC OPTICAL COMPONENTS AND PREPARATION THEREOF EPIGEM LTD (GB) 1995-04-13 WO claimed
US-20230365765-A1 Articles and Methods for Manufacture of Nanostructure Reinforced Composites NAWA AMERICA INC (US) 2023-11-16 US disclosed
WO-2023220475-A1 POLYMERIC SYSTEM FOR GENE DELIVERY REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2023-11-16 WO disclosed
WO-1996035971-A2 MICRO RELIEF ELEMENT AND PREPARATION THEREOF EPIGEM LIMITED (GB) 1996-11-14 WO disclosed
EP-0722387-A1 ORGANIC OPTICAL COMPONENTS AND PREPARATION THEREOF Epigem Limited (GB) 1996-07-24 EP disclosed
WO-1995009726-A1 ORGANIC OPTICAL COMPONENTS AND PREPARATION THEREOF EPIGEM LTD (GB) 1995-04-13 WO disclosed