Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821095 | 0.85 | PLA2G2A (0.60) | PLA2G2AKMT2ALMNAPPARGTSHR | |
| SCHEMBL3855495 | 0.84 | PLA2G2A (0.65) | PLA2G2AKMT2ALMNATSHRMAPK1 | |
| SCHEMBL3855156 | 0.84 | GRIK2 (0.50) | PLA2G2AKMT2ALMNAPPARGTSHR | |
| SCHEMBL31222301 | 0.84 | CYP19A1 (0.60) | PLA2G2AKMT2ALMNAMAPK1MEN1 | |
| SCHEMBL2244878 | 0.84 | CYP19A1 (0.60) | PLA2G2AKMT2ALMNAMAPK1MEN1 | |
| SCHEMBL10067377 | 0.82 | MAPT (0.57) | KMT2APPARGTSHRMEN1TDP1 | |
| SCHEMBL11289374 | 0.80 | CYP19A1 (0.66) | PLA2G2AKMT2ALMNATSHRMAPK1 | |
| SCHEMBL2246814 | 0.80 | CYP19A1 (0.70) | PLA2G2AKMT2AMAPK1MEN1ALDH1A1 | |
| SCHEMBL27734727 | 0.78 | PPARG (0.74) | KMT2APPARGMEN1TDP1THRB | |
| SCHEMBL17969632 | 0.78 | NPC1 (0.51) | PLA2G2AKMT2ALMNAMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582773-B2 | Substituted phenyl indoles | WYETH (US) | 2009-09-01 | — | — | US | disclosed |
| US-20050070592-A1 | Substituted phenyl indoles | WYETH (US) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070592-A1 | Substituted phenyl indoles | TPH2, IDO2, AANAT | PLA2G2A 3821/4885KMT2A 582/4885LMNA 3791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.