Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 11/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3854526 | 0.84 | PLA2G2A (0.59) | PLA2G2AKMT2ALMNATSHRMAPK1 | |
| SCHEMBL3852409 | 0.83 | PLA2G2A (0.46) | PLA2G2AKMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL3853087 | 0.82 | PLA2G2A (0.49) | PLA2G2AKMT2ALMNAALDH1A1 | |
| SCHEMBL9583415 | 0.82 | SMN1; SMN2 (0.67) | PLA2G2AKMT2ALMNAPLA2G1BMAPK1 | |
| SCHEMBL6821095 | 0.82 | PLA2G2A (0.60) | PLA2G2AKMT2ALMNAPTGS2PLA2G1B | |
| SCHEMBL8877224 | 0.80 | PLA2G2A (0.59) | PLA2G2APTGS2 | |
| SCHEMBL2244878 | 0.80 | CYP19A1 (0.60) | PLA2G2AKMT2ALMNAMAPK1KDM4E | |
| SCHEMBL31222301 | 0.80 | CYP19A1 (0.60) | PLA2G2AKMT2ALMNAMAPK1KDM4E | |
| SCHEMBL8298301 | 0.80 | PLA2G2A (1.00) | PLA2G2A | |
| SCHEMBL8292054 | 0.80 | PLA2G2A (0.70) | PLA2G2ALMNAPTGS2PLA2G1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582773-B2 | Substituted phenyl indoles | WYETH (US) | 2009-09-01 | — | — | US | disclosed |
| US-20050070592-A1 | Substituted phenyl indoles | WYETH (US) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070592-A1 | Substituted phenyl indoles | TPH2, IDO2, AANAT | PLA2G2A 3821/4885KMT2A 582/4885LMNA 3791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.