Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 1.00 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 6/20 | 0.55 |
| ▸ | MAOA | P21397 | 5/20 | 0.55 |
| ▸ | PRKCI | P41743 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30137886 | 1.00 | PBRM1 (1.00) | PBRM1HSD17B1MAOBMAOAPRKCI | |
| SCHEMBL385554 | 0.88 | PBRM1 (0.78) | PBRM1HSD17B1MAOBMAOAPRKCI | |
| SCHEMBL29983572 | 0.88 | PBRM1 (0.78) | PBRM1HSD17B1MAOBMAOAPRKCI | |
| SCHEMBL5145478 | 0.88 | PBRM1 (0.78) | PBRM1HSD17B1MAOBMAOAPRKCI | |
| Hydrochloric Acid SCHEMBL6531236 | 0.84 | PBRM1 (0.72) | PBRM1HSD17B1MAOBMAOAPRKCI | |
| SCHEMBL389710 | 0.83 | MAOB (0.78) | PBRM1HSD17B1MAOBMAOAPRKCI | |
| SCHEMBL7637788 | 0.81 | PBRM1 (0.68) | PBRM1HSD17B1MAOBMAOAPRKCI | |
| SCHEMBL6428269 | 0.80 | PBRM1 (0.67) | PBRM1HSD17B1MAOBMAOAPRKCI | |
| SCHEMBL27286 | 0.78 | PBRM1 (0.64) | PBRM1HSD17B1MAOBMAOATYMS | |
| SCHEMBL29804236 | 0.78 | PBRM1 (0.64) | PBRM1HSD17B1MAOBMAOATYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 365 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406242-B1 | PROCESS FOR THE PREPARATION OF RAMELTEON | IND CHIMICA SRL (IT) | 2013-06-05 | — | — | EP | claimed |
| US-8242291-B2 | Process for the preparation of ramelteon | INDUSTRIALE CHIMICA S.R.L. (IT) | 2012-08-14 | — | — | US | claimed |
| EP-2406242-A1 | PROCESS FOR THE PREPARATION OF RAMELTEON | Industriale Chimica S.R.L. (IT) | 2012-01-18 | — | — | EP | claimed |
| WO-2010103553-A1 | PROCESS FOR THE PREPARATION OF RAMELTEON | INDUSTRIALE CHIMICA S.R.L. (IT) | 2010-09-16 | — | — | WO | claimed |
| US-20100234622-A1 | PROCESS FOR THE PREPARATION OF RAMELTEON | INDUSTRIALE CHIMICA S.R.L (IT) | 2010-09-16 | — | — | US | claimed |
| US-20070238893-A1 | Asymmetric hydrogenation of acyl enamides | TEVA PHARMACEUTICAL INDUSTRIES LTD (IL) | 2007-10-11 | — | — | US | claimed |
| WO-2007056403-A2 | ASYMMETRIC HYDROGENATION OF ACYL ENAMIDES | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-05-18 | — | — | WO | claimed |
| US-20260146026-A1 | COMPOUND, COMPOSITION, CURED PRODUCT, METHOD FOR PRODUCING CURED PRODUCT, AND METHOD FOR PRODUCING ELECTRONIC COMPONENT | ADEKA CORPORATION (JP) | 2026-05-28 | — | — | US | disclosed |
| US-20260008796-A1 | INDANONE DERIVATIVES AS NUCLEOBASE BUILDINGS BLOCK FOR ON-DNA ALDEHYDE CAPTURE | UNIV GUELPH (CA) | 2026-01-08 | — | — | US | disclosed |
| US-12449428-B2 | On-demand electrochemical reactions in nano-electrospray ionization mass spectrometry for biomolecular analysis | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2025-10-21 | — | — | US | disclosed |
| EP-4610254-A1 | COMPOUND, COMPOSITION, CURED PRODUCT, METHOD FOR PRODUCING CURED PRODUCT, AND METHOD FOR PRODUCING ELECTRONIC COMPONENT | ADEKA CORPORATION (JP) | 2025-09-03 | — | — | EP | disclosed |
| US-20250205204-A1 | Transcription Factor Brn2 Inhibitory Compounds for Use as Therapeutics | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2025-06-26 | — | — | US | disclosed |
| CN-120019045-A | Compound, composition, cured product, method for producing cured product, and method for producing electronic component | 株式会社艾迪科 | 2025-05-16 | — | — | CN | disclosed |
| US-5167696-A | Pre- and postemergence | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-01 | — | — | US | disclosed |
| EP-0513387-A1 | ACTIVE OXYGEN INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-19 | — | — | EP | disclosed |
| EP-0453066-A1 | Indanderivatives | ZENECA LIMITED (GB) | 1991-10-23 | — | — | EP | disclosed |
| EP-0184809-B1 | IMIDAZOLYLALKOXYINDANIC DERIVATIVES, A PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | FERRER INTERNACIONAL, S.A. (ES) | 1989-08-02 | — | — | EP | disclosed |
| US-4610998-A | Imidazolylethoxyindanes and use as antithrombotic agents | FERRER INTERNACIONAL, S.A. (ES) | 1986-09-09 | — | — | US | disclosed |
| EP-0184809-A1 | Imidazolylalkoxyindanic derivatives, a process for preparing them and pharmaceutical composition containing them | FERRER INTERNACIONAL, S.A. (ES) | 1986-06-18 | — | — | EP | disclosed |
| EP-0043971-A1 | Indanoneoxyalkylpiperazine derivatives, the preparation thereof and pharmaceutical compositions containing the same | BASF Aktiengesellschaft (DE) | 1982-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260146026-A1 | COMPOUND, COMPOSITION, CURED PRODUCT, METHOD FOR PRODUCING CURED PRODUCT, AND METHOD FOR PRODUCING ELECTRONIC COMPONENT | CBR3, CBR1, NOTUM | PBRM1 1314/4885HSD17B1 602/4885MAOB 878/4885 |
| US-20070238893-A1 | Asymmetric hydrogenation of acyl enamides | NAAA, AADAC, IDH2 | PBRM1 3614/4885HSD17B1 2291/4885MAOB 1366/4885 |
| US-20100234622-A1 | PROCESS FOR THE PREPARATION OF RAMELTEON | CYP2B6, CYP2A6, UGT1A6 | PBRM1 2096/4885HSD17B1 1578/4885MAOB 1377/4885 |
| US-20260008796-A1 | INDANONE DERIVATIVES AS NUCLEOBASE BUILDINGS BLOCK FOR ON-DNA ALDEHYDE CAPTURE | TOP1, TOP2A, OGG1 | PBRM1 2275/4885HSD17B1 2825/4885MAOB 1210/4885 |
| US-20250205204-A1 | Transcription Factor Brn2 Inhibitory Compounds for Use as Therapeutics | BRDT, BRPF3, BRIX1 | PBRM1 256/4885HSD17B1 2757/4885MAOB 4036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.