Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.32 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384545 | 0.92 | KDM4E (0.42) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL384207 | 0.89 | KDM4E (0.41) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL4346448 | 0.86 | KDM4E (0.40) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL4349665 | 0.84 | KDM4E (0.40) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL21636814 | 0.84 | KDM4E (0.45) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL114535 | 0.83 | KDM4E (0.49) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL30863652 | 0.83 | KDM4E (0.49) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL4343369 | 0.82 | KDM4E (0.40) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL12112877 | 0.82 | KDM4E (0.34) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL29454971 | 0.82 | P2RX7 (0.34) | KDM4EL3MBTL1MEN1KMT2ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032556-B1 | ANTHRANILIC ACID DIAMIDE DERIVATIVE WITH HETERO-AROMATIC AND HETERO-CYCLIC SUBSTITUENTS | BAYER IP GMBH (DE) | 2015-07-22 | — | — | EP | disclosed |
| US-8946236-B2 | Anthranilic acid diamide derivative with hetero-aromatic and hetero-cyclic substituents | BAYER CROPSCIENCE AG (DE) | 2015-02-03 | — | — | US | disclosed |
| US-8946236-B2 | Anthranilic acid diamide derivative with hetero-aromatic and hetero-cyclic substituents | BAYER CROPSCIENCE AG (DE) | 2015-02-03 | — | — | US | disclosed |
| US-8946236-B2 | Anthranilic acid diamide derivative with hetero-aromatic and hetero-cyclic substituents | BAYER CROPSCIENCE AG (DE) | 2015-02-03 | — | — | US | disclosed |
| US-20130324560-A1 | ANTHRANILIC ACID DIAMIDE DERIVATIVE WITH HETERO-AROMATIC AND HETERO-CYCLIC SUBSTITUENTS | BAYER CROPSCIENCE AG (DE) | 2013-12-05 | — | — | US | disclosed |
| US-8536092-B2 | Anthranilic acid diamide derivative with hetero-aromatic and hetero-cyclic substituents | BAYER CROPSCIENCE AG (DE) | 2013-09-17 | — | — | US | disclosed |
| US-8536092-B2 | Anthranilic acid diamide derivative with hetero-aromatic and hetero-cyclic substituents | BAYER CROPSCIENCE AG (DE) | 2013-09-17 | — | — | US | disclosed |
| US-20120094830-A1 | ANTHRANILIC ACID DIAMIDE DERIVATIVE WITH HETERO-AROMATIC AND HETERO-CYCLIC SUBSTITUENTS | BAYER CROPSCIENCE AG (DE) | 2012-04-19 | — | — | US | disclosed |
| US-20120094830-A1 | ANTHRANILIC ACID DIAMIDE DERIVATIVE WITH HETERO-AROMATIC AND HETERO-CYCLIC SUBSTITUENTS | BAYER CROPSCIENCE AG (DE) | 2012-04-19 | — | — | US | disclosed |
| US-20120094830-A1 | ANTHRANILIC ACID DIAMIDE DERIVATIVE WITH HETERO-AROMATIC AND HETERO-CYCLIC SUBSTITUENTS | BAYER CROPSCIENCE AG (DE) | 2012-04-19 | — | — | US | disclosed |
| US-8101550-B2 | Anthranilic acid diamide derivative with hetero-aromatic and hetero-cyclic substituents | BAYER CROPSCIENCE AG (DE) | 2012-01-24 | — | — | US | disclosed |
| US-8101550-B2 | Anthranilic acid diamide derivative with hetero-aromatic and hetero-cyclic substituents | BAYER CROPSCIENCE AG (DE) | 2012-01-24 | — | — | US | disclosed |
| US-20100029478-A1 | ANTHRANILIC ACID DIAMIDE DERIVATIVE WITH HETERO-AROMATIC AND HETERO-CYCLIC SUBSTITUENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-02-04 | — | — | US | disclosed |
| US-20100029478-A1 | ANTHRANILIC ACID DIAMIDE DERIVATIVE WITH HETERO-AROMATIC AND HETERO-CYCLIC SUBSTITUENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-02-04 | — | — | US | disclosed |
| CN-101466702-A | Anthranilic acid diamide derivatives with heteroaromatic and heterocyclic substituents | BAYER CROPSCIENCE AG (DE) | 2009-06-24 | — | — | CN | disclosed |
| WO-2007144100-A1 | ANTHRANILIC ACID DIAMIDE DERIVATIVE WITH HETERO-AROMATIC AND HETERO-CYCLIC SUBSTITUENTS | BAYER CROPSCIENCE AG (DE) | 2007-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029478-A1 | ANTHRANILIC ACID DIAMIDE DERIVATIVE WITH HETERO-AROMATIC AND HETERO-CYCLIC SUBSTITUENTS | DDT, ANTXR2, QDPR | KDM4E 1199/4885L3MBTL1 1964/4885MEN1 1727/4885 |
| US-20120094830-A1 | ANTHRANILIC ACID DIAMIDE DERIVATIVE WITH HETERO-AROMATIC AND HETERO-CYCLIC SUBSTITUENTS | DDT, ANTXR2, QDPR | KDM4E 1199/4885L3MBTL1 1964/4885MEN1 1727/4885 |
| US-20130324560-A1 | ANTHRANILIC ACID DIAMIDE DERIVATIVE WITH HETERO-AROMATIC AND HETERO-CYCLIC SUBSTITUENTS | DDT, ANTXR2, QDPR | KDM4E 1199/4885L3MBTL1 1964/4885MEN1 1727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.