Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.73 |
| ▸ | MMP9 | P14780 | 10/20 | 0.73 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | MMP1 | P03956 | 1/20 | 0.65 |
| ▸ | MMP3 | P08254 | 1/20 | 0.65 |
| ▸ | MMP7 | P09237 | 1/20 | 0.65 |
| ▸ | MMP13 | P45452 | 1/20 | 0.65 |
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL561565 | 0.96 | MMP2 (0.71) | MMP2MMP9ADAMTS4TDP1ADAMTS5 | |
| SCHEMBL433897 | 0.96 | MMP2 (0.71) | MMP2MMP9ADAMTS4TDP1ADAMTS5 | |
| Chloromethane SCHEMBL7649372 | 0.96 | MMP2 (0.75) | MMP2MMP9ADAMTS4TDP1ADAMTS5 | |
| SCHEMBL1203540 | 0.96 | MMP2 (0.79) | MMP2MMP9ADAMTS4TDP1ADAMTS5 | |
| SCHEMBL697476 | 0.96 | MMP2 (0.79) | MMP2MMP9ADAMTS4TDP1ADAMTS5 | |
| SCHEMBL697477 | 0.96 | MMP2 (0.79) | MMP2MMP9ADAMTS4TDP1ADAMTS5 | |
| Hydrochloric Acid SCHEMBL3839410 | 0.95 | MMP2 (0.77) | MMP2MMP9ADAMTS4TDP1ADAMTS5 | |
| Hydrochloric Acid SCHEMBL11133046 | 0.95 | MMP2 (0.77) | MMP2MMP9ADAMTS4TDP1ADAMTS5 | |
| SCHEMBL8965755 | 0.94 | MMP9 (0.69) | MMP2MMP9ADAMTS4TDP1ADAMTS5 | |
| Hydrochloric Acid SCHEMBL28872216 | 0.93 | MMP2 (0.75) | MMP2MMP9ADAMTS4TDP1ADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7588887-B2 | Stable isotope metabolic labeling for analysis of biopolymers | THE REGENTS OF THE UNIVERSITY OF WASHINGTON (US) | 2009-09-15 | — | — | US | disclosed |
| US-20050003375-A1 | Stable isotope metabolic labeling for analysis of biopolymers | UNIVERSITY OF WASHINGTON (US) | 2005-01-06 | — | — | US | disclosed |
| US-6653076-B1 | Determining the rate of synthesis by incubating cells and monomers to allow their incorporation; isolating at different times and calculating the difference between abundance of monoisotopic and isotopomeric peaks | THE REGENTS OF THE UNIVERSITY OF WASHINGTON | 2003-11-25 | — | — | US | disclosed |
| WO-2000013025-A1 | STABLE ISOTOPE METABOLIC LABELING FOR ANALYSIS OF BIOPOLYMERS | UNIVERSITY OF WASHINGTON (US) | 2000-03-09 | — | — | WO | disclosed |