SCHEMBL561565

SCHEMBL561565

CC(=O)Cl.Cc1ccc(S(=O)(=O)NC(Cc2ccccc2)C(=O)O)cc1

nearest known ligand 0.71

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 10/20 0.71
MMP9 P14780 9/20 0.71
ADAMTS4 O75173 1/20 0.71
TDP1 Q9NUW8 1/20 0.71
ADAMTS5 Q9UNA0 1/20 0.67
ALDH1A1 P00352 1/20 0.67
MAPT P10636 1/20 0.67
POLB P06746 1/20 0.67
MMP3 P08254 2/20 0.64
MMP13 P45452 2/20 0.64
MMP1 P03956 1/20 0.64
MMP7 P09237 1/20 0.64
CTSL P07711 1/20 0.57
CA2 P00918 1/20 0.56
CA7 P43166 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL433897 1.00 MMP2 (0.71) MMP2MMP9ADAMTS4TDP1ADAMTS5
SCHEMBL3856155 0.96 MMP2 (0.73) MMP2MMP9ADAMTS4TDP1ADAMTS5
Chloromethane SCHEMBL7649372 0.95 MMP2 (0.75) MMP2MMP9ADAMTS4TDP1ADAMTS5
SCHEMBL1203540 0.95 MMP2 (0.79) MMP2MMP9ADAMTS4TDP1ADAMTS5
SCHEMBL697477 0.95 MMP2 (0.79) MMP2MMP9ADAMTS4TDP1ADAMTS5
SCHEMBL697476 0.95 MMP2 (0.79) MMP2MMP9ADAMTS4TDP1ADAMTS5
Hydrochloric Acid SCHEMBL11133046 0.93 MMP2 (0.77) MMP2MMP9ADAMTS4TDP1ADAMTS5
Hydrochloric Acid SCHEMBL3839410 0.93 MMP2 (0.77) MMP2MMP9ADAMTS4TDP1ADAMTS5
SCHEMBL8965755 0.93 MMP9 (0.69) MMP2MMP9ADAMTS4TDP1ADAMTS5
Hydrochloric Acid SCHEMBL28872216 0.92 MMP2 (0.75) MMP2MMP9ADAMTS4TDP1ADAMTS5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0720657-B1 BIOLOGICALLY RELEVANT METHODS FOR THE RAPID DETERMINATION OF STERILITY 3M INNOVATIVE PROPERTIES CO (US) 2007-08-15 EP claimed
CN-117858728-A Chelating compounds for the treatment of substance use disorders and uses thereof 可利尔科学公司 2024-04-09 CN disclosed
CN-116390748-A Compositions for preventing and treating influenza infection and methods of use thereof 佐治亚大学研究基金会股份有限公司 2023-07-04 CN disclosed
WO-2023106811-A1 ANTIVIRAL COMPOSITION COMPRISING COTTONSEED EXTRACT, AND PREPARATION METHOD THEREFOR 전남대학교산학협력단 2023-06-15 WO disclosed
CN-112195148-B Serum-free suspension-adapted MDCK cell and application thereof in preparation of influenza virus vaccine 上海生物制品研究所有限责任公司 2023-01-03 CN disclosed
CN-112195148-A Serum-free suspension-adapted MDCK cell and application thereof in preparation of influenza virus vaccine 上海生物制品研究所有限责任公司 2021-01-08 CN disclosed
CN-107530368-A Anticancer composition and use thereof 高雄医学大学 2018-01-02 CN disclosed
EP-3047274-A2 PSA ENZYMATIC ACTIVITY: A NEW BIOMARKER FOR ASSESSING PROSTATE CANCER AGGRESSIVENESS Ohmx Corporation (US) 2016-07-27 EP disclosed
WO-2015042493-A2 PSA ENZYMATIC ACTIVITY: A NEW BIOMARKER FOR ASSESSING PROSTATE CANCER AGGRESSIVENESS OHMX CORPORATION (US) 2015-03-26 WO disclosed
US-20140322740-A1 PSA PEPTIDASE ACTIVITY (PPA) AS A PROSTATE CANCER BIOMARKER NORTHWESTERN UNIVERSITY, AN ILLINOIS NOT FOR PROFIT CORPORATION (US) 2014-10-30 US disclosed
WO-1997028185-A1 ANTI-MICROBIAL PROTEIN COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (as a participant in the COOPERATIVE RESEARCH CENTRE FOR PLANT PATHOLOGY) (AU) 1997-08-07 WO disclosed
US-5616485-A GENETIC ENGINEERING CANGENE CORPORATION (CA) 1997-04-01 US disclosed
EP-0731841-A1 PROTEASES FROM STREPTOMYCES AND USE THEREOF IN PROTEIN EXPRESSION SYSTEMS Cangene Corporation (CA) 1996-09-18 EP disclosed
EP-0720657-A1 BIOLOGICALLY RELEVANT METHODS FOR THE RAPID DETERMINATION OF STERILITY NORTH AMERICAN SCIENCE ASSOCIATES INCORPORATED (US) 1996-07-10 EP disclosed
US-5486459-A Biologically relevant methods for the rapid determination of sterility MEDICAL COLLEGE OF OHIO (US) 1996-01-23 US disclosed
WO-1995017512-A2 PROTEASES FROM STREPTOMYCES AND USE THEREOF IN PROTEIN EXPRESSION SYSTEMS CANGENE CORPORATION (CA) 1995-06-29 WO disclosed
WO-1995008639-A1 BIOLOGICALLY RELEVANT METHODS FOR THE RAPID DETERMINATION OF STERILITY NORTH AMERICAN SCIENCE ASSOCIATES, INC. (US) 1995-03-30 WO disclosed
US-5159060-A Cytotoxic boronic acid peptide analogs MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 1992-10-27 US disclosed
US-5106948-A Anticarcinogenic agents MAO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 1992-04-21 US disclosed
US-4963655-A ANTITUMOR AGENTS; VIRICIDES, AIDS, HERPES; ANTICANCER AGENTS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 1990-10-16 US disclosed